GU Flashcards
1
Q
Abiraterone
A
Inhibitor of 17, 20 lyase and 17 alpha hydroxylase
Indications: locally recurrent CSPC, MCSPC, MCRPC
AE: hepatotoxicity, hypertension, requires coadministration of prednisone
2
Q
Enzalutamide / darolutamide
A
Androgen receptor antagonist
AE: weakness, increased risk of falls, seizure
3
Q
Apalutamide
A
Androgen receptor antagonist
AE: loss of muscle mass, no increased, seizure risk
4
Q
Radium
A
Alpha, particle emission
Indicated only in symptomatic metastatic prostate cancer with bone pain
5
Q
Enfortumab vedotin
A
Nectin 4 target