GU Flashcards

1
Q

Abiraterone

A

Inhibitor of 17, 20 lyase and 17 alpha hydroxylase

Indications: locally recurrent CSPC, MCSPC, MCRPC

AE: hepatotoxicity, hypertension, requires coadministration of prednisone

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2
Q

Enzalutamide / darolutamide

A

Androgen receptor antagonist

AE: weakness, increased risk of falls, seizure

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3
Q

Apalutamide

A

Androgen receptor antagonist

AE: loss of muscle mass, no increased, seizure risk

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4
Q

Radium

A

Alpha, particle emission

Indicated only in symptomatic metastatic prostate cancer with bone pain

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5
Q

Enfortumab vedotin

A

Nectin 4 target

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