Hematology Flashcards
1
Q
Crizanlizumab
A
P selection inhibition
Indication: refractory SCD pain crises
2
Q
Voxalitor
A
Increases Hb oxygen affinity
Indication: refractory pain crises in HbSS
3
Q
Efgartigimod
A
Inhibits Fc receptor -> increases antibody clearance
Indication - refractory ITP
4
Q
Fostamatinib
A
MOA - syk inhibition
INDICATION - refractory ITP
5
Q
FEIBA
A
Indication hemophilia A w/ inhibitor
Functionally an aPCC with VIIIa
6
Q
Activated r VIIa
A
Indication - hemophilia a or B with inhibitor
7
Q
Emicizumab
A
MOA - complexes IXa with X (pseudo tenase)
INDICATION - ppx fox hemophilia A
8
Q
Eculizumab
A
Terminal c5 inhibitor
9
Q
Ravulizumab
A
Long acting c5 inhibitor
10
Q
Deferiprone AE
A
Agranulocytosis
11
Q
Deferasirox AE
A
- renal failure and GI upset