Tissues And Organs Flashcards
What holds cells together? (4)
- Cell to cell adhesion molecules
- Extracellular matrix proteins
- internal external scaffolding
- pressure caused by close proximity
What do epithelial cells line?
All cavities and free surface
Organ definition
More than 1 tissue coming together
What do epithelia rest on?
Supporting bed of connective tissue
Which attaches the epithelial layer to other tissue
What are the lateral surface adherence systems in epithelia? (3)
Tight junctions
Desmosome
Gap junctions
What are the basal surface adherence systems in epithelia? (5)
Hemi desmosome
Focal adhesions
Integrins
Role of tight junctions
Where are they found? (2)
Prevent movement of large molecules through lumen into deep tissue layers
Intestines
Blood brain barrier
What is paracellular transport?
When solvent move across an epithelial cell layer through the tight junctions between cells
Role of adhesion junctions
What are they made of?
How are they found?
Tissue stability and transport barrier - adhesion belt
Intracellular actin filaments
In pairs
What is the strongest method of adhesion?
Desmosome
What is the function of desmosome?
Where are they found?
Mechanical strength and prevent tissue destrucitons
Tissue that experiences mechanical stress - like the skin
Function of gap junctions
Where are they found?
Communicate changes in intercellular molecular composition - allows free movement of small molecules, allows waves of electrical impulses
Cardiac and smooth muscle cells
What attaches a hemidesomsome to the basal lamina?
Role?
Intergrin
Anchors epithelial cells to basal lamina and prevents loss to external surface
What is the basal lamina attached to?
Connective tissue
Function of basal surface focal adhesion?
What links cells to the basement membrane?
Anchor actin filaments to the basement membrane
Integrins
Name the three types of muscle cells
Skeletal
Cardiac
Smooth