Tissue Repair

Question 1

STEP ONE

Answer 1

Inflammation

1. Inflammator chemical release by
   a) mast cells –> histamine
   b) macrophages and injured cells –> others
2. Capillaries dilate and become permeable
3. White blood cells, clotting proteins, antibodies diffuse to injured area
4. Clot forms
5. Portion exposed to air forms scab
6. Excess fluids, destroyed cells and debris is picked up by lymph vessels or macrophages

Question 2

RICE

Answer 2

Rest
Ice
Compress
Elevate

Question 3

2 ways

Answer 3

1. Regeneration
   Destroyed tissue replaced with SAME kind of tissue
2. Fibrosis
   Destroyed tissue replaced with DIFFERENT kind of tissue (scar tissue)

Question 4

STEP TWO

Answer 4

Organization

1. Granulation tissue- replaces blood clot
   a. Capillaries to form new network
   b. Fibroblasts produce collagen
   c. Macrophages digest clot
2. Granulation tissue is destine to become scar tissue

Question 5

STEP THREE

Answer 5

Regeneration and fibrosis

1. Surface epithelium regenerates
2. Epithelial cells migrate across the granulation tissue below scab
3. Fibrosis tissue beneath matures and contracts

Question 6

6 factors affecting blood supply

Answer 6

1. Adequacy of blood supply
2. Type of tissue injured
3. Type of injury and immediate care given
4. Nutrition
5. State of health
6. Age

Question 7

Repair of various tissue types (best to worst)

Answer 7

1. Epithelial
2. Bone and most fibrous connective
3. Smooth muscle and dense regular
4. Skeletal muscle and cartilage
5. Cardiac and nervous