Tissue organisation revision

Question 1

nuclear pore

Answer 1

made of subunits - annular, luminal, ring and column

Question 2

perinuclear space

Answer 2

space between the inner and outer membrane of the nuclear envelope

Question 3

relationship between the perinuclear space and the ER lumen

Answer 3

continuous

Question 4

where is peripheral heterochromatin

Answer 4

lines the inner side if the nuclear envelope

Question 5

difference in morphology between rough and smooth ER

Answer 5

rough is flattened

smooth is tubular

Question 6

a stack of ERs is called a…

Answer 6

cisternae

Question 7

size of vesicles from the golgi

Answer 7

they contain macromolecules and are >50nm

Question 8

diameter of microtubules

Answer 8

20nm

Question 9

what are microtubules made of

Answer 9

polymers of alpha and beta tubulin

Question 10

intermediate filaments

Answer 10

connect desmosomes via cytokeratins
concerned with mechanical strength and stabilisation of the nuclear envelope
each cell type has a different kind of IF
polymers of filamentous proteins forming rope like structures

Question 11

types of intermediate fibres

Answer 11

cytokeratins
vimentins
neurofilamentous proteins

Question 12

microfilaments

Answer 12

filamentous (F-actin) or monomeric (G-actin)

most dense in the periphery

Question 13

sarcomas

Answer 13

cancers of the mesenchymal cells

Question 14

examples of mesenchymal cells

Answer 14

fibroblasts, osteoclasts, chondrocytes

Question 15

cell to cell junctions

Answer 15

zonulae - continuous belts eg tight junctions and adhesion belts
maculae - discrete spots eg desmosomes

Question 16

action of tight junctions

Answer 16

seal paracellular pathways

regulation of cell polarity

Question 17

adhesion belts

Answer 17

basal to tight junctions 
function as master junction 
cadherins associated with adhesion belts interact with actin microfilaments

Question 18

does mitosis occur in absorbative epithelia

Answer 18

yes

cells undergo constant renewal from crypts

Question 19

where is exocrine solution from

Answer 19

luminal plasma membrane