Skin

Question 1

List the order of tissues in skin

Answer 1

stratum cornea - epidermis - papillary dermis - reticular dermis - hypodermis - subcutis

Question 2

Recall the features in skin

Answer 2

basement membrane
keratinocytes in different layers
apendigeal structures: pilo subaceous unit
hair follicles
hair shafts
sebaceous gland - release sebem - oily
pilo errector muscle
apocrine and eccrine glands - sweat
meissner’s corpuscles - nerve ending involved in sensation
collagen
fibroblasts
langerhans cell - APC
merkel cell - sensory - on basement membrane
melanocyte - dendritic - on basement membrne

Question 3

What are skin’s functions

Answer 3

biggest organ 
protective - infection/wound /radiation/UV 
vitamin D production 
sensory organ 
thermoregulation 
waterproof 
cosmetics

Question 4

How is the integrity of skin maintained

Answer 4

The epidermis and dermis are joined by hemidesmosomes and tonofilaments which are cell junctions
If these proteins are affected it casues the skin to blister

Question 5

How do melanocytes develop

Answer 5

dendritic cell

Have vacuoles in them

Question 6

what is the function of melanocytes

Answer 6

produce melanin - protects keratinocyte’s DNA from UV radiation

Question 7

how are melanocytes regulated

Answer 7

UV radiation
keratinocytes release melanocyte stimulating hormone
melanocytes produce melanin in melanosome
moves via dendritic processes to keratinocytes