Tissue Nematodes Flashcards
In which class is Trichinella spiralis classified?
Adenophorea
What is characteristic of Trichinella spiralis’ esophagus?
long = 2/3 of body length: anterior is thin walled & muscular vs. posterior is surrounded by stichocytes (granular cells w/ digestive enzymes)
What is the stichosome and what does it secrete?
posterior to esophagus & stichocytes. secretes?
Where do adult Trichinella spiralis’ live in the host?
small intestine
Explain how one host ind is the DH & IH in the life cycle of Trichinella spiralis.
female produces L1 not eggs
What does ovoviviparous mean?
produces L1 not eggs
What type of cells do Trichinella spiralis L1 penetrate once they have left the SI?
skeletal muscle fibers & induce change in muscle
What changes occur in a host cell during its transformation into a nurse cell in Trichinella spiralis?
- loses myofilaments 2. nuclei hypertraply 3. mitochondria degenerate 4. circulatory rate - network of capillaries
What symptoms might the host experience during nurse cell transformation in Trichinella spiralis infection?
muscle pain
Compare sylvatic & urban trichinellosis.
sylvatic: wild carnivores & prey vs. urban: farms, rats & pigs, pigs eat rats and humans eat pigs
What are the 3 phases of Trichinella spiralis pathology?
- intestinal phase 2. migration phase 3. inflammatory phase
What happens during the intestinal phase of Trichinella spiralis?
mild: lesions in intestinal lining, nausea, fever, diarrhea, pain
What happens during the migration phase of Trichinella spiralis?
severe (L1s): eye tongue, diaphragm, jaw, chewing, swallowing all have muscle pain. difficultly breathing, chewing, swallowing
What happens during the inflammatory phase of Trichinella spiralis?
moderate: nurse cells, strong immune response, heart damage & nervous disorder
How is infection with Trichinella spiralis diagnosed?
ELISA: 1. antibodies produced against parastie 2. antigen from stichocytes
What is ESA and where is it produced?
excretory secretory antigen from stichocytes