Tim Green Flashcards
What is a drug?
a chemical compound
What is a medicine?
It contains a drug in a suitable formulation
What does ADME stand for?
absorption, distribution, metabolism and excretion
Source of the drug: willow tree
aspirin
Source of the drug: chinchona
quinine
Source of the drug: poppy
morphine
Source of the drug: belladonna (deadly nightshade)
atropine
Source of the drug: foxglove
Digitalis (treatment of heart failure)
Source of the drug: coca
cocaine (led to local anaesthetics)
Source of the drug: Marijuana
Cannabis
Source of the drug: nicotinia
Nicotine
Source of the drug: Yew
Paclitaxel(anticancer agent)
Source of the drug: Pregnant mare’s urine
Premarin (menopause treatment)
What was the earliest source of therapeutic agents?
natural products
Which of these drugs was developed most recently?
a) antibiotics
b) anti-virals
c) arsenicals
d) beta-blockers
b
What do agonists do?
bind to the receptor and cause a response
what do antagonists do?
bind to the receptor. They have no effect themselves, but prevent agonists from binding and so therefore block the response.
To which of the following are receptors NOT directly linked? A. G-proteins B. kinases C. ion channels D. phosphatases
D
Where might an agonist bind? A. DNA B. enzyme C. receptor D. ion channel
C
An agonist binds to its receptor and has
no effect
What is L-DOPA used to treat?
Parkinson’s disease
