Terry Gleave Flashcards
what happens if the sodium/potassium pump gets poisoned?
it stops working
Na+ voltage gated ion channels are either:
open, closed or closed&inactive
Unipolar sensory neurons have…
one long axon which connects receptors to the spinal cord or brain
multipolar, inter and motor neurons have
many dendrites and one axon
Bipolar neurons have
one dendrite and one axon
What is the equilibrium potential for K+?
-90mV
Alan L. Hodgkin and Andrew F. Huxley won a Nobel Prize in Physiology/Medicine in 1963. Wha did they record in 1939?
They first recorded the resting potential from living neuron - Squid giant axon (0.5mm in diameter)
The threshold is when
the membrane potential becomes more positive than at rest and depolarisation reaches a trigger point
At threshold, what is generated?
an action potential
As the axon hillock depolarizes, which voltage gated ion channels open rapidly?
Na+
Conduction velocity is the speed of…?
Action potential
1-20m/s is the speed of what?
an impulse that travels along neurons
What does the speed of conduction depend on?
The diameter of a fiber (bigger AP= faster), temperature and whether or not it is myelinated
What is saltatory conduction?
Where action potentials jump between nodes of Ranvier under myelination.
A fibres are
large myelinated axons that conduct action potential at the speed 15-120 m/s
B fibres are
medium diameter myelinated axons that conduct the action potential at the speed 3-15 m/s
C fibres are
unmyelinated axons that conduct the action potential at the speed <3 m/s
Electrical synapses are
extremely rare, have direct contact between cells (gap junctions) and are located in CNS and PNS.