Tiivistelmä Flashcards
They aimed?
To identify optimum neuropsychological measures for characterizing PPA, examine the relationship between behavioural change and subtypes of PPA and to determine whether characteristic profiles of language, working memory, and behavioural changes occur in PPA.
How many patient?
Forty-seven patients with PPA and multi-domain Alzheimer’s disease (AD) together with 19 age-matched controls underwent a large battery of working memory and language tests.
They found?
that simple tasks of sentence ordering, narrative production, and buccofacial praxis were particularly useful in differentiating non-fluent/agrammatic variant PPA (nfvPPA) from other PPA subtypes.
Which test was useful in detecting semantic dementia?
test of single word comprehension
for logopenic variant PPA (lvPPA) relative to nfvPPA?
No individual tests were discriminating for logopenic variant PPA (lvPPA) relative to nfvPPA.
LvPPA and multidomain AD exhibited?
similar language profiles.
A principal components analysis revealed that?
characteristic PPA profiles extended beyond the realms of language, in particular, the presence of apraxia in nfvPPA, behavioural changes in SD, and working memory deficits in lvPPA.
These findings suggest that?
not all tests are equally discriminatory for PPA and highlight the importance of a test profile in differentiating PPA. These results also support the view that lvPPA is a focal form of AD and emphasize the difficulties classifying lvPPA.
