Behavioural Data Flashcards
Why behavioural data were absent from 7 patient?
This was either because the patient attended the appointment without an informant or else carers/relatives were distressed and it was deemed inappropriate to approach them.
Which group exhibited more behavioural changes than the other patient groups, except in the domain of eating and drinking
Patients with SD
in frequency of behavioural changes in SD patients with predominantly right and predominantly left-sided atrophy there was?
No difference.
Behavioural changes were ? to SD?
not exclusive to SD and some patients in each group exhibited changes in each category of behaviour evaluated.
What was the only expectation?
The only exception was that no patient with lvPPA exhibited altered ‘response to environment’.
Group differences reached significance for the following behavioural domains: ?
response to environment’ (Fisher’s exact test, p = .018), ‘social behaviour’ (Fisher’s exact test, p = .038) and ‘hobbies, order and routine’ (Fisher’s exact test, p = .015).
Changes in ‘hobbies, order and routine’ were more common in ?
SD than nfvPPA, lvPPA, and AD
and changes in patients’ ‘response to their environment’ were more common ?
in SD than lvPPA.
Changes in ‘social behaviour’ were more common in SD than ?
AD.
changes in these behavioural domains had relatively high sensitivities and specificities for SD
A large proportion of patients with nfvPPA, lvPPA, and AD exhibited ?
withdrawal in social behaviours and interaction with others, in particular, a relatively high proportion of lvPPA (44.4%) and nfvPPA (40.0%) patients enjoyed being with others less.
In contrast, a high proportion of SD patients enjoyed
being with others more (42.9%).
Changes in social emotions were more prevalent in
nfvPPA and SD patients than in lvPPA or AD.
The majority of SD patients (57.1%) showed reduction in ? And increase?
showed a reduction in the range of food they eat and an increase in the following features: reaction to painful stimuli (66.7%), clockwatching (57.1%), simple (71.4%) and complex (66.7%) repetitive behaviours, following a daily routine (57.1%), and enjoyment of puzzles (71.4%).
an increase in these features ( reaction to pain stimuli, clockwatching, repetitive behaviours etc.) occurred in the other patient groups?
Rarely.
Nevertheless just under a third of nfvPPA patients liked TV quizzes and sweet food more than previously.
Fourteen patients had missing data on at least one of the 25 test variables due ?
to anxiety/ the magnitude of their difficulties and had to be excluded from the PCA.
The remaining 33 patients comprised ?
9 nfvPPA, 7 lvPPA, 7 SD, and 10 multi-domain AD.
Which factor did not yield group differences?
Factor two = Tests of verbal/phonological working memory loaded heavily onto factor two.
Patients with nfvPPA scored significantly lower on factor ?
factor one (the ‘speech production/grammaticality’ factor) than patients in the other groups and
Patients with SD scored higher on factor ?
three (the ‘semantic/behaviour’ factor) than patients with nfvPPA, lvPPA, or AD
Scores for factors 1–3 for the 33 patients were entered into a LDA to determine ?
how well the factors derived from the PCA were able to differentiate the three diagnostic groups
How many discriminant functions were obtained?
Three.
How many discriminant functions
were statistically significant ?
Two of three.
The discriminant model correctly classified ?
72.7% of patients (88.9% of nfvPPA patients, 42.9% of lvPPA patients, 71.4% of SD, and 80.0% of multi-domain AD patients
The model showed 88.9% sensitivity and 100.0% specificity for diagnosing
NfvPPA
The sensitivity for diagnosis of SD was
71,4% with a specificity of 96.2%.
The sensitivity for diagnosis of lvPPA was ?
42,9% with a specificity of 96.2%.
The sensitivity for diagnosis of multi-domain AD was
80.0% with a specificity of 69.6%.
Two patients with SD were predicted to be in the ?
AD group
One patient with nfvPPA was predicted to be in the
AD group
Four patients with lvPPA were predicted to be in the ?
AD group
One patient with AD was predicted to be in the ?
lvPPA group and a further patient with AD was predicted to be in the SD group.
While the model using the three factors was reasonably accurate at classifying ? it was unable to distinguish between the ?
nfvPPA and SD,
multi-domain AD and lvPPA groups
