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Micro > Ticket and Viro > Flashcards

Ticket and Viro Flashcards

1
Q

Which of the following bacteria is named after an investigator of typhus who was a victim of this disease?
a. Rickettsia akari
b. Ehrlichia erwingii
c. Rickettsia prowazekii
d. Ehrlichia chaffeensis

A

C

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2
Q

Which of the following antimicrobials should not be used in treating RMSF? a. Doxycycline
b. Fluoroquinolones
c. Trimethoprim-sulfamethoxazole
d. Chloramphenicol

A

C

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3
Q

Which of the following is also known to be an extrahuman reservoir of endemic typhus causative agent in the US?
a. Flying squirrel louse
b. Mites
c. Rat flies
d. Soft ticks
e. Hard ticks

A

A

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4
Q

Identify the presumptive disease based in the Weil-Felix reaction. [OX-19 positive; OX-2 negative; OXK negative]
a. Epidemic typhus
b. Scrub typhus
c. Q fever
d. RMSF
e. Endemic typhus

A

E

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5
Q

Which of the following is considered as reservoir host of rickettsialpox causative agent?
a. Wild rodents
b. Hard ticks
c. Humans
d. Dogs
e. None of the choices
6. All of the following infection

A

A

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6
Q

All of the following infections manifest the presence of eschar, EXCEPT
a. Flea-borne spotted fever
b. Boutonneuse fever
c. Rickettsialpox
d. Endemic typhus

A

D

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7
Q
  1. Scrub typhus develops suddenly after 10-day incubation period with severe headache, fever and body pain. Which of the following vector can caused the above-mentioned disease?
    a. Rat fleas
    b. Chiggers
    c. Hard ticks
    d. Soft ticks
    e. Human louse
A

B

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8
Q

Which of the following infections exhibits a small ulcer with a black crust at the site of a tick bite?
a. Rickettsialpox
b. Murine typhus
c. Rocky mountain spotted fever
d. Brill-Zinsser disease
e. Mediterranean spotted fever

A

E

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9
Q

Q fever is characterized by both acute and chronic infections. Endocarditis is the most common form of chronic infections which is associated with which antigenic phase of the organism?
a. Phase 1
b. Phase 2
c. Phase 3
d. Phase 4

A

A

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10
Q

Why is it necessary to process suspected specimens with C burnetii at BSL-3?
a. It can cause severe pneumoniae
b. The treatment is difficult due to because it is dependent on the phase of infection
c. It is acquired via inhalation
d. All of the choices

A

C

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11
Q
  1. All of the following statements are true about C. burnetii, EXCEPT
    a. The organism multiplies within vacuoles
    b. Doxycycline is the drug of choice for acute infections
    c. It is transmitted primarily by arthropod-bites
    d. It is the causative agent of Q fever
    e. Small obligate organisms similar to GN bacteria
A

C

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12
Q

mountaineer from Costa Rica took a hike through a forested and brushy area near his home. The next morning, he noticed and removed a large insect from his thigh. About 7 days later, he experienced an abrupt onset of fever and malaise. He now seeks medical attention because he is concerned about a possible infection transmitted by the tick. Which of the following is known to be vector of the disease process?
a. Rat flea
b. Wood tick
c. Human body louse
d. Lone star tick
e. Chigger
13. All of the follo

A

B

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13
Q

Which of the following histopathological cell is common in patients with RMSF?
a. Bacteria located intracellularly
b. Intracellular vacuoles
c. Morulae within neutrophils
d. Perivascular lymphocytes
e. Morulae within monocytes

A

A

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14
Q

All of the following are TRUE about the Ricketssia, EXCEPT
i. Fastidious and obligate extracellular bacteria
ii. Cannot be culture using cell free media
iii. Multiply via transverse fission
iv. Humans are only accidental host except R. prowazekii
a. III and IV
b. I and III
c. II and IV
d. IandII

A

B

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15
Q

Ehrlichiae and chlamydiae resembles each other, however they differ in
a. Cell wall synthesis
b. ATP synthesis
c. Nuclei acid synthesis
d. Protein synthesis

A

B

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16
Q
  1. All of the following statements regarding R. akari are correct EXCEPT
    i. It causes rickettsialpox
    ii. Ticks of the genus Amblyomma are responsible for transmission
    iii. The disease is mild
    iv. Disease is more common in urban than in rural areas
    a. I
    b. II
    c. III
    d. IV
    e. None of the choices
A

B

17
Q

Observing typical morulae in granulocytic leukocytes confirm that the patient is infected with
a. E. chaffeensis
b. C. burnetii
c. R. rickettsia
d. A. phagocytophilum

A

A

18
Q

Since C. burnetii can be transmitted by milk when animals like cows and goats are infected, what is the best sterilization method to destroy viable organisms?
a. Autoclaving
b. Filtration
c. Boiling
d. Radiation
e. High temperature, short time Pasteurization

A

E

19
Q
  1. Identify the presumptive organism based on the Weil-Felix reaction. [OX-19-negative; OX-2- negative; OXK-positive]
    a. R. prowazekii
    b. O. tsutsugamushi
    c. R. akari
    d. R. rickettsia
    e. C. burnetii
A

B

20
Q

Ricketssial organisms are recovered in blood. What is the ideal time of collection for testing?
a. Decline period
b. Incubation period
c. Period of illness
d. Prodromal period
e. Convalescent period

A

E

21
Q

This disease is a recrudescence of an old typhus infection
a. Q fever
b. Trench fever
c. Rickettsialpox
d. Brill-Zinsser disease

A

D

22
Q

Which of the following infectious disease is often mistaken as rickettssialpox?
a. Anthrax
b. Syphilis
c. Rocky mountain spotted fever
d. Herpes
e. Measles

A

D

23
Q

Which of the following is the principal vector of endemic infection?
a. Xenopsylla cheopsis
b. Dermacentor andersonii
c. Leptotombidum delicense
d. Pediculus humanus corpons

A

A

24
Q

All of the following laboratory tests can be employed in diagnosing HME and HGE, EXCEPT
a. Platelet
b. CBC with WBC differential count
c. Urinalysis
d. SGPT/ ALT
e. None of the choices

A

C

25
Q
  1. Which of the following diagnostic tests is most widely used in diagnosing rickettsial infections?
    a. Weil Felix test
    b. Complement fixation
    c. Polymerase Chain Reaction
    d. Cell culture using cell lines
    e. Indirect immunofluorescence and enzyme immunoassay
A

E

26
Q

diseased characterized by malaise, headache, rigors and fever developed in members of several families living in an unheated war-damaged house in an Eastern European country. Erythematous 2-6 mm macular red rashes appeared on the people’s trunks and later their extremities. Some of the people had coughs. The presumptive diagnosis is epidemic typhus. What is the hallmark of infection of rickettsial infections?
a. Low grade fever
b. Contact dermatitis
c. Vasculitis
d. Headache and body malaise
e. All of the choices

A

D

27
Q

Which of the following statements is not true about R. prowazekii life cycle?
a. Scratching the area of the bite allows the rickettsia excreted in the feces to penetrate the skin
b. Rickettsiae are transmitted from one generation of lice to another
c. The louse obtains the organism by biting infected human beings and transmits the agent by fecal
excretion on the surface of the skin of another person
d. Whenever a louse bites, it defecates at the same time

A

B

28
Q

Which specific structure is responsible for the ability of Rickettsia to adhere endothelial cells?
a. Glycocalyx
b. Outermembrane protein A
c. Lipopolysaccharides
d. Pili and fimbrae

A

B

29
Q

Which of the following antimicrobial is known to be the treatment of choice for Ehrlichiae?
a. Doxycycline
b. Fluoroquinolones
c. Trimethoprim-sulfamethoxazole
d. Chloramphenicol
e. Penicillin G

A

A

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