Myco Flashcards
Drug of choice for most Mycoplasma infections
a. Ampicillin
b. Doxycycline
c. Penicillin G
d. Clindamycin
B
Which of the following clinical disease is caused by Mycoplasma pneumoniae?
a. Ventilator associated pneumonia
b. Interstitial pneumonia
c. Eosinophilic pneumonia
d. Malignant pneumonia
e. Parapneumonic effusion
f. Community acquired pneumonia
F
The infectious stage of Chlamydia
a. Reticulate body
b. Intermediate body
c. Elementary body
d. Nobody
C
This can cause post-partum fever and pneumonia in premature newborns
a. M. genitalium
b. M. pneumoniae
c. M. hominis
d. None
C
The most common symptom of C. pneumoniae function a. Cervicitis
b. Pharyngitis
c. Conjunctivitis d. Proctitis
B
Bacterial vaginosis
Gardnerella vaginalis
Chancre
Treponema pallidium
Chancroid
Haemophilus ducreyi
Mucopurulent cervicitis
Neisseria gonorrhea
Lymphogranuloma venereum
Chlamydia trachomatis
Which of the following Rickettsia species presents a gradual onset of clinical symptoms?
a. R. prowazekii
b. R. typhi
c. R. rickettsia
d. R. akari
e. None
B
Which diagnostic test is used to detect morulae formation of anaplasmosis?
a. Immunoenzymes stain
b. Giemsa stain
c. Cell culture
d. Serologic tests
B
The vector of scrub typhus is
a. Ixodes ticks
B. Chigger
c. Hard ticks
d. Soft ticks
B
Which of the following does NOT belong to classical signs and symptoms of Ehrlichiosis?
a. Increased WBC count
b. Decreased platelet count
c. Elevated serum ALT
d. Elevated serum transaminases
A
Identify which rickettsial infection based on the Weil-Felix test, [OX19=pos; OX2= pos; OXK= neg]
a. RMSF
b. Endemic typhus
c. Epidemic typhus
d. Q fever
e. Ehrlichiosis
A
The drug of choice for C. burnetii chronic infection is
a. Doxycycline alone
b. Doxycycline + fluoroquinolones
c. Doxycycline + hydroxyquinolone
d. Doxycycline + hydroxychloroquine
D
Which Rickettsial infection presents rash in centrifugal manner?
a. Rocky mountain spotted fever (RMSF)
b. Brill-Zinsser disease (R. prowazekii)
c. Endemic (Murine) typhus
d. Flea-borne spotted fever
B
the following are possible complications associated with Q fever
b. Pneumonia
c. Subacute bacterial endocarditis
d. Kidney failure
D
What virulence factor aids Rickettsia species to adhere endothelial cells?
a. Fimbriae
b. Outer membrane proteins
c. 54 kDa surface proteins
d. Flagella
e. Capsule
B
All of the following exhibits maculopapular rashes, EXCEPT
a. R. conorii
b. R. rickettsii
c. R. prowazekii
d. R. akari
D
The following are signs of congenital syphilis EXCEPT a. Periostitis
b. Hepatitis
c. Keratitis
B
All of the following are used as treatment for early infection of Lyme Disease EXCEPT a. Doxycycline
b. Cefixime
C. Cefuroximr
D. Amoxicillin
B
In secondary syphilis, condylomas appear in these body parts EXCEPT a. Anogenital region
B.Axillae
C.Back
D. Mouth
C
Among the following drugs, which can be added to BSK II as a complex liquid medium to grow B. burgdorferi?
a. Amphotericin A
b. Isoniazid
c. Rifampin
C
Which of the following among specimens used for agglutination tests in the determination of Leptospirosis?
a. Tissues b. CSF
c. Serum d. Urine
C
The inflammation in primary syphilis infection is characterized by the predominance of these types of cells
a. Lymphocytes and plasma cells
b. Eosinophils and basophils
c. Lymphocytes and macrophages
A
Which of the following organisms principally infects the liver and kidneys?
a. Borrelia burgdorferi
b. Leptospira interrogans
c. Treponema pallidum
d. Borrelia recurrentis
B
This marks the stage 1 of Lyme Disease
a. Erythema migrans
b. Chancre
c. Chanroid
d. Erythema marginatum
A
Which of the following is a characteristic of Leptospira?
a. 5-15 um long, 0.1-0.2 um wide
b. 10-30 um long, 0.3 um wide
c. 10-30 um long, 0.5 um wide
A
Medications believed to be effective in the treatment of relapsing fever includes all of the following EXCEPT
a. Penicillin
b. Tetracycline c. Amoxicillin d. Erythromycin
C
the Two-tiered test for Lyme disease, which test is used for Screening?
1. In
a. Gram staining
b. Enzyme immunoassay
c. Western blot
d. Culture using Barbour-Stoenner-Kelly med
B
Which of the following statements is true?
a. Leptospira and Borellia are the only known pathogens of family spirochaetaceae
b. BoreIlia species belongs to the family spirochaetaceae
c. The flagella is invested above the outer membrane
d. Spirochetes do not contain peptidoglycan which differs from gram + bacteria
B
The purpose of adding 5-fluorouracil in culturing Leptospira organism
a. All of the above
b. To suppress the growth of non-pathogenic serovars
c. To eliminate of fungal growth
d. To prevent the growth of treponema
B
Which of the following is true for the stages of Syphilis?
a. Secondary syphilis is characterized by localized chancre and regional lymphadenopathy
b. Tertiary syphilis is highly infectious
c. Primary syphilis is characterized by condylomata lata
d. Majority of latent syphilis will not progress to tertiary syphilis
D
Which of the following is true for Relapsing fever?
a. Antibodies appear during afebrile phase sb
b. Abrupt rise in the temperature after 1 week incubation
c. Can be caused by Borrelia burgdorferi
B
The following are True for the Non-treponemal test in the detection of Syphilis, EXCEPT?
a. RPR test can serum to determine and evaluate neurosyphilis
b. Can be used to determine for evaluation of titers of antibodies
c. It can be used to monitor efficacy of therapy
d. Can have false positive result due to other infections
C
Lyme disease is caused by these spirochetes
a. Borrelia recurrentis
b. Borrelia burgdorferi
c. Borrelia hermsii
B
Erythema migrans is the characteristic skin lesion of this disease
a. Lyme disease
b. Whipples’ disease
c. Weils disease
A
Which of the following species is Louse borne?
a. Borrelia recurrentis
b. Borrelia vincenti
c. Borrelia bermsii
d. Borrelia burgdorferi
A
A 24 years old man was wading in flood water since yesterday up to today after the heavy rain, he sought consultation at the SHH OPD. What prophylaxis should be given?
a. Doxycycline 100 mg/cap, 2 capsules to be given once a week until the end of exposure, 72
hours within exposure
b. Doxycycline 100 mg/cap, 1 capsule to be given daily within 72 hours of exposure
c. Doxycycline 200 mg/cap, 1 capsule to be given daily within 72 hours of exposure
d. Doxycycline 100 mg/cap, 2 capsules to be given daily within 72 hours of exposure
A
When visualized under dark field microscopy, it is characterized as tightly coiled, thin, flexible spirochetes, with very fine spirals and one end is often bent, forming a hook.
a. Treponema pallidum
b. Borrelia burgdorferi
c. Leptospira interrogans
d. Borellia recurrentis
C
Jarisch-Herxheimer reaction is characterized by the following manifestations, EXCEPT?
a. Purpura
b. Lymphadenopathy c. Fever
d. Urticaria
A
This stage of Lyme disease is characterized by arthralgia and neurologic manifestations
a. Stage 4
b. Stage 2
c. Stage 1
d. Stage 3
B
True for the Treponemal test in the detection of Syphilis
a. It detects the presence of Treponemal antigen in the specimen
b. It utilizes Cardiolipin as reagent
c. It is persistently positive in Latent Syphilis
d. It detects the presence of Anti-treponemal Antibodies in the specimen
C
Which of the following is correctly paired according to the epidemiology of Lyme disease?
a. Ixodes pacificus= Eastern United State
b. Ixodes scapularis= Europe
c. Ixodes ricinus= West coast United states
d. Ixodes dammini= Northeast United States
D
Which of the following organisms can be seen in the blood as a specimen with the use of aniline dyes? a. Leptospira
b. None
c. Treponema d. Borrelia
D
patient from Connecticut, USA came in at the emergency room dm/to facial paralysis associated with painful radiculopathy. History showed he was a deer hunter and was treated and completed the oral antibiotic due to fever which happened 2 weeks ago. In this case, what antibiotic should be given?
a. Ceftriaxone
b. Penicillin
c. Amoxicillin d. Doxycycline
A
A man came in with Fever and Neurologic deficit and seizure, History revealed he has been wading in floodwaters 7 days prior. Which statement is true to support your diagnosis?
a. Agglutinate test is the confirmatory test for such case
b. There is a good prognosis for this case
c. Urine is the specimen of choice for this case
d. Doxycycline 100 mg/tab, to be taken once a day is the treatment modality
A
Which of the following can be stained best with silver impregnation technique for visualization of the organism?
a. Treponema pallidum
b. Leptospira interrogans
c. Borrelia vincentii
d. Borrelia burgdorferi
e. Borellia recurrentis
A
Sudoku is caused by this spirochete:
a. Borrelia buccalis
b. Spirillum minor
c. Borrelia burgdorferi
d. Borrelia refringes
B
A 17 year old boy who works at Cebu Safari as caretaker of Moluccan, Major Mitchell and Bare-eyed Cockatoo. When he developed fever, chills and flu-like illness after 10 days. What is the drug of choice?
a. Doxycycline
b. Erythromycin
c. Trimethoprim-sulfamethozaxole
d. Penicillin G
A
Which of the following organism can spread through vertical route of transmission (Mother to fetus)
a. Chlamydia trachomatis
b. Chlamydia psittaci
c. Mycoplasma pneumoniae
d. Chlamydia pneumoniae
A
A 6 years old child had lacrimation and mucopurulent discharge of the eye. The older sibling also got
the same condition a few days ago. What is the causative serovariant?
a. C trachomatis serovar C
b. C trachomatis serovar D
c. LGV1
d. C trachomatis serovar E
e. LGV2
A
A determinant of the pathogenicity of Mycoplasma
a. Ability to resist sulfonamides
b. Presence of plasmid
c. Adhesion factor
d. The number of serovars
C
To treat bacterial vaginosis among pregnant patients, Metronidazole administration is restricted to the 1st and 2nd trimester
a. True
b. False
B
Which Chlamydial serotype is/are involved in patient presenting with a painful inflammation and enlargement of the inguinal lymph nodes above and below the inguinal ligament? 3pts
L2
L3
E
F
L1
D
L1
Pseudobubo
Donovanosis
Groove sign
Lymphagranuloma venereum
Henderson-Patterson bodies
Molluscum contagiosium
Bubo formation
Chancroid
Painless ulcer
chancre
A woman complained of vaginal discharge and dysuria. Cytobrush culture on cell McCoy cell culture showed Positive for inclusion bodies. What is the serovariant?
a. LGV2
b. C trachomatis serovar A
c. C trachomatis serovar E
d. LGV3
e. C trachomatis serovar B
C
Which of the following organism’s inclusion bodies will be stained dark with iodine?
a. Chlamydia pneumoniae
b. Chlamydia psittaci
c. Chlamydia trachomatis
d. None of them
C
Characteristic feature of pneumonia caused by Chlamydia pneumoniae
a. Eosinophilia b. Neutrophilia c. Monocytosis d. Basophilia
A
Chlamydia infection is the most common sexually transmitted bacterial pathogen
a. True
b. False
A
Clue cells
Gardnerella vaginalis
School of fish
Haemophilus ducreyi
Koilocytes
Human Papilloma Virus
Donovan bodies
Klebsiella granulomatis
Gram negative intracellular bacteria
Neisseria gonorrhoeae
When the Chlamydias are stained with routine gram staining procedure, they will look like?
a. Gram positive Bacilli
b. Gram variable Rods
c. Gram negative Pleomorphic
d. Gram Negative Rods
C
woman who had just given birth had an onset of fever and body malaise after she got discharged from the hospital. Ultrasound showed tubo-ovarian abscess. The OBgyne specialist ordered culture of
the abscess which showed a fried egg colony appearance. What is the causative organism?
a. Mycoplasma genitalium
b. Mycoplasma hominis
c. Mycoplasma pneumoniae
d. Ureaplasma urealyticum
B
The DNA and RNA content is equally distributed in the EB. The reason why Elementary Bodies are colored Purple with Giemsa stain is?
a. The nucleoid has more DNA than the cytoplasm
b. The DNA is more concentrated in the nucleoid
c. The cytoplasm has more RNA than the nucleoid
d. The RNA is more concentrated in the nucleoid
B
True for Mycoplasma organism
a. Obligate intracellular pathogens
b. Resistant to penicillin and erythromycin
c. Can reproduce in cell free media
d. Ability to grow in Cell line culture media
C
A woman complained of vaginal discharge associated with inguinal lymph node enlargement. McCoy cell culture of the cytobrush showed positive for inclusion bodies. What is the causative serovariant?
a. C trachomatis serovar K
b. C trachomatis serovar E
c. C trachomatis serovar B
d. LGV 1
e. C trachomatis serovar A
f. LGV4
D
The hallmark feature of Hemolytic anemia in Mycoplasma pneumoniae infections
a. Red blood cell hemolysis due to intracellular parasitism
b. The cross reactivity of the organism specific antibodies with that of the red blood cell
c. The production of Cold agglutinins which are autoantibodies that targets red blood cell
d. The production of Cytokines which triggers a heightened immature response against red bleed cell
C
woman who had sexual contact with a man whom she met in a club in a week ago is now complaining of vaginal discharge and dysuria. Gynecological finding showed cervical motion tenderness and non-foul smelling whitish discharge. The culture of the discharge in A8 agar showed growth with a change in the color of the medium after 2 days of incubation. What is the causative organism?
a. Mycoplasma pneumoniae
b. Mycoplasma hominis
c. Mycoplasma genitalium
d. Ureaplasma urealyticum
D
True of Chlamydia, EXCEPT
a. Obligate intracellularly pathogens
b. The species which infects human have common group antigens
c. Are gram negative bacteria
d. Multiply intracellularly
D
