Thyroid physiology Flashcards
which hormone is released at hypothalamus?
thyroid releasing hormone
which hormone is released at ant. pituitary?
thyroid stimulating hormone
what connect hypothalamus to ant. pituitary?
nerves or blood
blood
thyroid stimulating hormone goes to what organ?
thyroid gland
thyroid stimulating hormone stimulated what transporter at the thyroid gland?
NaI transporter
NaI transporter function?
take iodine into thryoid
thyroid precursor is called what?
thyroglobulin
what process converts thyroglobulin into thyroid hormone?
iodination
what must you add to thyroglobulin to turn into thyroid hormones?
iodine
tumour marker for thyroid gland?
thyroglobulin
full names of two main thyroid hormones?
thyroxine
triiodothyronine
short names of the two main thyroid hormones?
t4
t3
which thyroid hormone is most common in blood?
t4 - thyroxine
t3 is aka?
triiodothyronine
which thyroid hormone has longer half life?
t4 - thyroxine
which thyroid hormone has is more active?
t3 - triiodothyronine
which thyroid hormone has one less iodine?
t3 - triiodothyronine
which thyroid hormone gives more -ve feedback?
t4 - thyroxine
thyroid hormones travel through to blood to target cells,
which thyroid hormones converts into which?
t4 converts to t3
normal thyroid levels is called what?
Euthyroidism
which chemical can inhibit the NaI transporter?
perchlorate
% of t4 compared to t3 in blood
t4 - 90%
t3 - 10%
functions of thyroid hormones (t4 and t3)
-4
- Regulates energy
- Metabolism
- Drives SNS
- ↑O2 consumption
examples of primary problems of the thyroid gland?
-4 main ones
graves
goitre’s
hashimoto’s
riedal
most common hyperthyroid cause?
grave’s
most common hypothyroid cause?
hashimoto’s
