Thyroid Pharmacology Flashcards

1
Q

Levothyroxine
MOA
PK
TU

A

MOA: T4 agonist
PK: steady state at 6-8 weeks
TU: hypothyroidism

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2
Q

Methimazole
MOA
TU

A

MOA: inhibit thyroid peroxidase
TU: Graves’

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3
Q

Propylthiouricyl
MOA
TU

A

MOA: inhibit thyroid peroxidase and deiodinase 1 (inhibits peripheral conversion of T4 -> T3)
TU: Graves’

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4
Q

Iodine
MOA
TU

A

MOA: high concentrations, inhibits iodine metabolism
TU: Graves’

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5
Q

123I
MOA
TU

A

MOA: radioactive iodine
TU: thyroid imaging

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6
Q

131I
MOA
TU

A

MOA: radioactive iodine
TU: thyroid ablation

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