Thyroid Pharmacology Flashcards
1
Q
Levothyroxine
MOA
PK
TU
A
MOA: T4 agonist
PK: steady state at 6-8 weeks
TU: hypothyroidism
2
Q
Methimazole
MOA
TU
A
MOA: inhibit thyroid peroxidase
TU: Graves’
3
Q
Propylthiouricyl
MOA
TU
A
MOA: inhibit thyroid peroxidase and deiodinase 1 (inhibits peripheral conversion of T4 -> T3)
TU: Graves’
4
Q
Iodine
MOA
TU
A
MOA: high concentrations, inhibits iodine metabolism
TU: Graves’
5
Q
123I
MOA
TU
A
MOA: radioactive iodine
TU: thyroid imaging
6
Q
131I
MOA
TU
A
MOA: radioactive iodine
TU: thyroid ablation