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CC2Lec VI > Thyroid Gland > Flashcards

Thyroid Gland Flashcards

1
Q

Major Component of Colloid

A

Thyroglobulin

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2
Q

Transport of Iodine is by

A

Sodium Iodine Symporter

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3
Q

Oxidation and binding of Iodide with Tyrosine results to

A

MIT and DIT

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4
Q

Oxidized and bound to tyrosyl residues

A

Concentrated Iodide

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5
Q

Enzyme for the formation of T3 and T4

A

Thyroid peroxidase

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6
Q

It signals the follicular cells to ingest microscopic droplets of colloid by endocytosis

A

TSH

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7
Q

Most potent or most active thyroid hormone

A

T3

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8
Q

Better indicator for the recovery and recurrence of hyperthyroidism

A

T3

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9
Q

Principal secretory product

A

T4

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10
Q

Good indicator of thyroid secretory rate

A

T4

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11
Q

Transports both T3 and T4

A

Thyroxine Binding Globulin

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12
Q

Transports only T4

A

Thryoxine Binding Pre Albumin (Transthyretin)

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13
Q

Transports what only left binds with albumin

A

Thyroxine Binding Albumin

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14
Q

Hypothalamic Pituitary Thyroid Axis

A

Trh Tsh Thyroid Hormones

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15
Q

Elevated level of circulating thyroid hormones

A

Hyperthyroidism

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16
Q

Symptoms of Hyperthyroidism

A

Tachycardia, tremors, heat intolerance, unexplained weight loss, emotional lability, menstrual changes

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17
Q

Elevated T3 and T4, low TSH

A

Primary Hyperthyroidism

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18
Q

Elevated T3 and T4 and TSH

A

Secondary Hyperthyroidism

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19
Q

Group of syndromes caused by increased Free thyroid hormones

A

Thyrotoxicosis

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20
Q

T3 Thyrotoxicosis

A

Increased ft3 normal ft4 low TSH

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21
Q

T4 Thyrotoxicosis

A

Normal or Low ft3, increased t4, low TSH

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22
Q

Clinical Features of Graves D

A

Exophthalmos and Pretibial Myxedema

23
Q

Diagnostic test of Graves D

A

TSH receptor antibody test

24
Q

Disorder wherein the thyroid turns into a woody or stony hard mass

A

Reidel Thyroiditis

25
Q

No clinical symptoms of Hyperthyroidism

A

Subclinical Hyperthyroidism

26
Q

Inflammation in the neck area and characterized by low grade fever

A

Subacute GranulomatousThyroiditis

27
Q

Symptoms of De Quervains Thyroiditis

A

Absent TPO antibodies, elevated Esr and thyroglobulin

28
Q

Insufficient amount of thyroid hormones

A

Hypothyroidism

29
Q

Treatment of Hypothyroidism

A

Levothyroxine

30
Q

Signs and symptoms of Hypothyroidism

A

Bradycardia, weight gain, coarsened skin, cold intolerance, mental dullness

31
Q

Iodine defficiency

A

Primary Hypothyroidism

32
Q

Use of Lithium will results to

A

Inhibits thyroidal iodine uptake

33
Q

Also known as Chronic autoimmune thyroiditis

A

Hashimotos Disease

34
Q

Relates to Goiter

A

Hashimotos Disease

35
Q

Laboratory Results of Hashimotos

A

Elevated TSH and Positive TPO antibody

36
Q

Non pitting swelling of the skin

A

Myxedema

37
Q

Deposition of mucopolysaccharides in the skin

A

Myxedema

38
Q

Stunted physical growth and mental retardation

A

Cretinism

39
Q

Defective development or function of the gland

A

Congenital Hypothyroidism

40
Q

Increased TSH

A

1 hypo, hashimotos thyroiditis, tsh antibodies, thyroid hormone resistance

41
Q

Decreased TSH

A

1 hyper, 2 3 hypo, treated graves disease, euthyroid sick disease, over replacement of thyroid hormone in hypo

42
Q

Ability of the thyroid gland to trap or uptake iodine

A

Radioactive Iodine Uptake

43
Q

Post operative marker of thyroid cancer

A

Tg Assay

44
Q

Thyrotoxicosis factitia

A

Decreased thyroglobulin

45
Q

Subacute thyroiditis

A

Increased thyroglobulin

46
Q

Product of removal of one iodine from the inner ring of T4

A

Reverse T3

47
Q

Elevation of RT3 is useful for

A

Euthyroid sick syndrome

48
Q

Indirectly measures the amount of free T4 in the blood

A

Free Thyroxine Index

49
Q

Aids in the identification between hyperthyroidism and euthyroidism

A

TBG

50
Q

Most accurate tool for the evaluation of the presence of thyroid nodules

A

FNA

51
Q

Test for the presence of residual or recurrent disease

A

Recombinant Human TSH

52
Q

Measure for anti thyroglobulin antibodies, RBC is specimen

A

Tanned Erythrocyte Hemagglutination

53
Q

Detection of residual thyroid metastasis in the MTC

A

Serum Calcitonin

CC2Lec VI (4 decks)

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