Thyroid Disorders Flashcards

1
Q

Hormone levels of Hypothyroidism

A

T3 + T4 ===> Reduced
FH4 ===> Reduced
TSH ===> Increased

Metabolism and Activity —> Reduced

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2
Q

Symptoms of Hypothyroidism

A
  • fatigue
  • weight gain
  • constipation
  • depression
  • dry skin
  • intolerance to cold
  • menstrual irregularities
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3
Q

What is the treatment for Hypothyroidism

A

1st Line:
Levothyroxine

Alternative:
Liothyronine

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4
Q

What is the difference between Levothyroxine and Liothyronine

A

Liothyronine has a more rapid onset and more potent

(non uk brands may not be bio-equivalent)

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5
Q

What is the monitoring required for starting Levothyroxine

A
  • monitor TSH every 3 months till stable then yearly
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6
Q

What point in the day should you take Levothyroxine

A

Morning 30 mins before food/drink

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7
Q

Why should you give similar brands for Levothyroxine and Liothyronine

A

because patients can experience side effects when switching

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8
Q

Hormone Level of Hyperthyroidism

A

T3 + T4 ===> Increased
FH4 ===> Increased
TSH ===> Reduced

Metabolism and Activity —> Increased

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9
Q

Symptoms of Hyperthyroidism

A
  • hyperactivity
  • Insomnia
  • Heat Intolerance
  • increased appetite
  • weight loss
  • Diarrhoea
  • goitre (swollen thyroid glands)
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10
Q

What is the Treatment for Hyperthyroidism

A

1st Line:
Carbimazole

2nd Line:
Propylthiouracil

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11
Q

What are the MHRA warnings for Carbimazole

A
  • Neutropenia
  • Congenital Malformation
  • Acute Pancreatitis
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12
Q

What should you be on while taking Carbimazole

A

Contraception (due to congenital malformation)

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13
Q

What should you report while taking Carbimazole

A
  • Sore throat (neutropenia)
  • severe abdominal pain (pancreatitis)
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14
Q

What can Propylthiouracil lead to

A

Liver Disorders
(jaundice, dark urine, nausea)

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15
Q

How to treat Hyperactivity symptoms of Hyperthyroidism

A

Beta Blockes

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16
Q

What is Grave’s Disease

A

an autoimmune condition where your immune system produces antibodies that cause the thyroid to produce too much thyroid hormone

17
Q

How to treat Grave’s Disease

A

1st Line:
Radioactive Iodine
or
Carbimazole

18
Q

Pregnancy and Hyperthyroidism Treatment: 1st Trimester

A

Propylthiouracil

19
Q

Pregnancy and Hyperthyroidism Treatment: 2nd and 3rd Trimester

A

Carbimazole