Thyroid Disorders Flashcards
Hormone levels of Hypothyroidism
T3 + T4 ===> Reduced
FH4 ===> Reduced
TSH ===> Increased
Metabolism and Activity —> Reduced
Symptoms of Hypothyroidism
- fatigue
- weight gain
- constipation
- depression
- dry skin
- intolerance to cold
- menstrual irregularities
What is the treatment for Hypothyroidism
1st Line:
Levothyroxine
Alternative:
Liothyronine
What is the difference between Levothyroxine and Liothyronine
Liothyronine has a more rapid onset and more potent
(non uk brands may not be bio-equivalent)
What is the monitoring required for starting Levothyroxine
- monitor TSH every 3 months till stable then yearly
What point in the day should you take Levothyroxine
Morning 30 mins before food/drink
Why should you give similar brands for Levothyroxine and Liothyronine
because patients can experience side effects when switching
Hormone Level of Hyperthyroidism
T3 + T4 ===> Increased
FH4 ===> Increased
TSH ===> Reduced
Metabolism and Activity —> Increased
Symptoms of Hyperthyroidism
- hyperactivity
- Insomnia
- Heat Intolerance
- increased appetite
- weight loss
- Diarrhoea
- goitre (swollen thyroid glands)
What is the Treatment for Hyperthyroidism
1st Line:
Carbimazole
2nd Line:
Propylthiouracil
What are the MHRA warnings for Carbimazole
- Neutropenia
- Congenital Malformation
- Acute Pancreatitis
What should you be on while taking Carbimazole
Contraception (due to congenital malformation)
What should you report while taking Carbimazole
- Sore throat (neutropenia)
- severe abdominal pain (pancreatitis)
What can Propylthiouracil lead to
Liver Disorders
(jaundice, dark urine, nausea)
How to treat Hyperactivity symptoms of Hyperthyroidism
Beta Blockes
