Osteoporosis Flashcards
What are the 3 main risk factors of osteoporosis
- Post menopausal women
- Men over 50 years old
- long term corticosteroids (glucocorticoids)
What is the treatment of Osteoporosis
Oral Bisphosphonates
- Alendronic acid
- Risdronate Sodium
When should you review Osteoporosis medication
5 years…
- Alendronic acid
- Risdronate Sodium
3 years…
- Zoledronic Acid
How to treat Glucocorticoid induced Osteoporosis
- Zoledronic Acid
- Denosumab
Alternative treatment for Osteoporosis in Men
- Zoledronic Acid
- Denosumab
- Strontium
Alternative treatment for Osteoporosis in Post Menopausal women
Young Menopausal
- HRT or Tibolone
If severe osteoporosis
- teriparatide
When would you start Osteoporosis treatment when giving glucocorticoids in women
–> >= 70 years old
–> previous fracture
–> large corticosteroid dose (prednisolone above 7.5 mg daily)
When would you start Osteoporosis treatment when giving glucocorticoids in Men
70 years old and either…
–> previous fracture
–> large dose glucocorticoid
When would you start Osteoporosis treatment when giving glucocorticoids in general
large dose corticosteroids for >3 months
What are the side effects of Bisphosphonates
- Atypical femoral fractures
- osteonecrosis jaw
- osteonecrosis of external auditory canal
- oesophageal reactions
What should you report for each side effect of Bisphosphonates: osteonecrosis jaw
report dental pain, swelling discharge
What should you report for each side effect of Bisphosphonates: Atypical femoral fractures
report thigh, hip and groin pain
What should you report for each side effect of Bisphosphonates: osteonecrosis of external auditory canal
report ear pain, discharge, ear infections
What should you report for each side effect of Bisphosphonates: oesophageal reactions
report throat irritation and heart burn
How to reduce oesophageal reactions when taking Bisphosphonates
take with full glass of water while standing
===> keep standing for 30 minutes after
