Thyroid Disease and Therapy Flashcards
two thyroid hormones
triiodothyronine (T3) and thyroxine (T4)
thyroid hormones effect
stimulate protein synths, increase glucose, mobilize fatty acid, decreased cholesterol, increase ATP consumption and basal metabolic rate
causes of hypothyroidism
thyroid gland destruction- hashimotos
pituitary disorder that inhibits TSH
hypothalamus lacks ability to secrete TRF
signs and symptoms of hypothyroidism
slow metabolism, constipation, weight gain, lethargy, coarse hair, irregular menses, myxedema
how hypothyroidism effects organ systems
cardiac- hypotension and bradycardia
MS- weak muscle
neuro- slow speech and depression
treatment for hypothyroidism
thyroid hormone replacement therapy
side effects of thyroid medications
increase BP and HR, increase metabolism, insomnia, tremors, HA, palpitations, diarrhea, sweating
causes of hyperthyroidism
tumors, autoimmune disorder- graves disease
sings and symptoms of hyperthyroidism
exophthalmos, hypertension, tachycardia, weight loss, fine hair, sweating
how hyperthyroidism affects other symptoms
cardiac- tachycardia, hypertension
thyroid- goter
MS- tremors
eyes- exophthalmos
tx of hyperthyroidism
iodide suppression, antithyroid drugs, thyroidectomy
side effects of antithyroid drugs
rash, fever, myalgia, jaundice, nausea, agranulocytosis
side effects of antithyroid drugs
rash, fever, myalgia, jaundice, nausea, agranulocytosis
goiter
enlarged thyroid gland
can be caused by hyper and hypo thyroidism