Thyroid Disease Flashcards
thyroid fxn
- regulate metabolism or the way the body uses energy
- regulated by feedback loop
what influences thyroid fxn?
thyroid hormone (thyroxine + triiodothyronine)
secretion of thyroid hormone feedback mechanism is mediated by
hypothalamic-pituitary-thyroid axis
what increases or decreases the feedback of thyroid hormone secretion?
metabolic demand
hyperthyroidism
excess T3 and T4 in blood
hyperthyroidism can cause what?
thyrotoxicosis
what is the most common effect of thyrotoxicosis?
Graves’ disease
syms of hyperthyrodism
- anxiety
- fatigue
- rapid HR
- heat intolerance
- weight loss
- exopthalmous
goal of med management of thyroid disease
euthyroid state
med management of hyperthyroidism
- antithyroid agents
- radioactive iodine
- surgery
antithyroid agents to manage hyperthyroidism
propylthiouracil, 18 months
radioactive iodine
destroys thyroid w/o physically removing it
hypothyroidism
inadequate amt of T3 and T4
syms of hypothyroidism
- slow physical/mental activity
- sensitivity to cold
- weight gain
med management of hypothyroidism
thyroid hormone replacement