COPD Flashcards
chronic obstructive pulmonary disease
IRREVERSIBLE chronic airflow obstruction for which no cure exists
COPD is a combo of what 2 disease processes?
- chronic bronchitis
- emphysema
chronic bronchitis
excessive bronchial mucous production
how long do pts have to cough for to be diagnosed with chronic bronchitits?
pt has to have chronic cough for 3 consecutive months within the last two years
how many Americans have COPD?
24 million
T/F: COPD is the 3rd leading cause of death in US
true
etiology of COPD
- smoking
- genetic susceptibility
- long-term exposure to occupational and environmental pollutants
genetic susceptibility of COPD
production of inflammatory mediators in response to smoke exposure
what changes in large airways are seen in pts with chronic bronchitis?
- thickened bronchial walls
- enlargement of mucous glands
what changes in small airways are seen in pts with chronic bronchitis?
narrowing, scarring, increased sputum production, mucous plugging, collapse of peripheral airways
T/F: chronic bronchitis obstructs inspiration
false
obstruction on inspiration AND expiration
pathophysiology of emphysema
- smoke injures lung parenchyma
- air spaces enlarge and lose elastic recoil
how does smoke injure lung parenchyma?
- alveolar epithelium is damaged
- inflammatory cells migrate to damage site
- cells release enzymes that destroy alveolar walls
T/F: emphysema obstructs expiration
true
complications of COPD
- progressive deterioration with periodic exacerbations
- progressive dyspnea
- recurrent pulmonary infections
- pulmonary hypertension
- thoracic bullae & pneumothorax