Thyroid Disease Flashcards
name some symptoms of hypothyroidism
> lethargy
feeling cold
constipation
heavy periods
name some signs of hypothyroidism
> weight gain > dry skin > bradycardia > slow reflexes > goitre > severe: puffy face, large tongue, hoarseness
what are symptoms of hyperthyroidism?
> anxiety > heat intolerance > bowel frequency > light periods > palpitations
what are signs of hyperthyroidism?
> weight loss > sweaty palms > hyperreflexia > goitre > thyroid eye symptoms
what type of hypothyroidism is this:
> raised TSH
> low FT4
> low FT3
primary
what type of hypothyroidism is this:
> raised TSH
> normal FT4 and FT3
subclinical
what type of hypothyroidism is this:
> Low TSH
> Low FT4 and FT3
secondary
name some congenital causes of primary hypothyroidism
> agenesis
> dyshormonogenesis (trapping/organification)
name an autoimmune cause of primary hypothyroidism
hashimotos thyroiditis
name some acquired causes of primary hypothyroidism
> autoimmune thyroid disease
iatrogenic
chronic iodine deficiency
post partum
what can cause secondary hypothyroidism?
> pituitary tumour
post pituititary surgery (radiotherapy)
craniopharyngioma
sheenans syndrome
what can cause tertiary hypothyroidism?
isolated TRH deficiency
how is hypothyroidism treated?
> levothyroxine tablets T4 (liothyronine T3)
initially 50mcg/day which is increased after 2 weeks to 100mcg
dose is increased until the TSH is normal
in hypothyroidism how often is TSH tested?
annually
in what situations would you treat hypothyroidism differently?
> ischaemic heart disease (start on lower dose)
pregnancy (increase dose)
postpartum thyroiditis (trail withdraw- measure in 6 weeks)
myxedema coma (rare may need IV T3)
