Thyroid And Parathyroid Histology Flashcards
Where does the thyroid gland store the hormones it produces?
Extracellularly
If a thyroid gland is really active, what type of epithelium does it have?
Columnar
If the thyroid gland is not active, what type of epithelium does it have?
Cuboidal
Name the disorder: Loss of feedback control by thyroid gland; bulging eyes, fine finger tremors, tachycardia; Goiter
Grave’s disease
Name the disorder: unto immune disease associated with hypo function of the thyroid gland; antibodies to thyroid per oxidase and thyroglobulin
Hashimoto’s disease
What cells in the follicular epithelium are derived from the neural crest and contain smal cytoplasmic granules and store the hormone calcitonin?
parafollicular cells or C cells
Name the hormone: Acts to decrease calcium concentration in the blood inhibiting bone resorption
Calcitonin
What does calcitonin bind to?
Receptors on osteoclasts
What stimulates calcitonin secretion?
Hypercalcemia
What pharyngeal pouches do parathyroid hormones develop in?
3 and 4
What are the 2 cell populations in the parathyroid gland?
Chief/principal cells and oxyphil/acidophilic cells
Which parathyroid cells secrete parathyroid hormone?
Chief cells
What histologically characteristic distinguishes the parathyroid gland from other endocrine glands?
It has fat deposits
When Ca binds to the CaSR of the parathyroid cell plasma membrane, what happens?
It suppresses parathyroid secretion
Parathyroid acts directly on what osteocyte?
OsteoBLASTS
