Thyroid Flashcards

1
Q

Type I deiodinase

A

Outer ring and inner ring
PRIMARY source of T3 in circulation

Liver, kidney, thyroid, skeletal muscle

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2
Q

Type II deiodinase

A

Outer ring
Makes T3 and rT3
Pituitary senses these levels and gives feedback

Brain, pituitary, placenta, cardiac muscle

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3
Q

Type III deiodinase

A

Inner ring
Only makes rT3
Brain, placenta, skin

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4
Q

BMR

Hypothyroid

A

Overall decreased

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5
Q

Carbohydrate metabolism

Hypothyroid

A

DEC gluconeogenesis
DEC glycogenolysis
Normal serum glucose

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6
Q

Protein metabolism

Hypothyroid

A

DEC synthesis

DEC proteolysis

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7
Q

Lipid metabolism

Hypothyroid

A

DEC lipogenesis
DEC lipolysis
IN serum cholesterol

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8
Q

Thermogenesis

Hypothyroid

A

Decreased

cold intolerant

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9
Q

BMR

Hyperthyroid

A

Overall increased

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10
Q

Carbohydrate metabolism

Hyperthyroid

A

IN gluconeogenesis
IN glycogenolysis
Normal serum glucose

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11
Q

Protein metabolism

Hyperthyroid

A

IN synthesis
IN proteolysis
Muscle wasting

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12
Q

Lipid metabolism

Hyperthyroid

A

IN lipogenesis
IN lipolysis
DEC serum cholesterol

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13
Q

Thermogenesis

Hyperthyroid

A

Increased

heat intolerant

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