GH/IGF-I Flashcards
1
Q
GH Effect on Adipose
A
DEC Glucose uptake
IN Lipolysis
Overall: DEC Adiposity
2
Q
GH Effect on Liver
A
IN RNA synthesis IN Protein synthesis IN Gluconeogenesis IN IGFBP IN IGFs
Overall: Create IGFs
3
Q
GH Effect on Muscle
A
DEC Glucose uptake
IN AA uptake
IN Protein synthesis
Overall: IN Lean body mass
4
Q
IGF-I Effect on; Kidney Pancreas Intestine Islets Parathyroids Skin Connective Tissue Bone Heart Lung
A
IN Protein synthesis
IN RNA synthesis
IN DNA synthesis
IN Cell size and number
Overall: IN Organ size
IN organ function
5
Q
IGF-I Effect on Chondrocytes
A
IN AA uptake IN Protein synthesis IN RNA synthesis IN DNAA synthesis IN Collagen IN Chondroitin sulfate IN Cell size and number
Overall: IN Linear growth
6
Q
GH Stimulators
A
GHRH Dopamine Norepi/Epi (exercise/stress) AA (protein building) Thyroid hormone
Stress, exercise, starvation
7
Q
GH Inhibitors
A
SS
IGF-I
Glucose (hyperglycemia)
FFA (obesity)
Decreased with aging, high blood glucose, obesity