Thromboembolitic Disease Flashcards

1
Q

According to Virchows triad which three things contribute to thromboembolitic disease?

A

Stasis

Increased coagubility

Endothelial damage

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2
Q

What are the symptoms of DVT?

A

OFTEN NONE

Pain

Swelling

Tenderness

Fever

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3
Q

What are the investigations for a DVT?

A

Doppler

D Dimer

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4
Q

What is the management of a DVT?

A

LMW heparin (clexane) until confirmed,

Then warfarin for 3/12 if the cause is known

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5
Q

What could be used to measure the likelihood of there being a DVT?

A

Wells score

eg, malignancy

Pitting oedema in symptomatic leg

Previous DVT

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6
Q

What does PE lead to?

A

Pulmonary infarction

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7
Q

What is this?

A

Wedge sign (PE)

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8
Q

What are the symptoms of PE?

A

They can range from none to sudden death

SOB

Tachypnoea

Pleuritic pain

Hyper/hypotension

Haemoptysis

Fever

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9
Q

What are the cardinal symptoms of PE

A

Tachynpnoea

Dysopnea

Pleuritic Pain

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10
Q

What are the classifications of PE?

A

Massive - Acute -Low CO, collapse, hypoxaemia, hypotension

Subacute - progressive occlusion and hypertension, hypoxaemia

Minor - SOB, pleuritic pain, haemoptysis and fever

Chronic - recurrent causing pulmonary hypertension and SOB

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11
Q

What are some risk factors for PE?

A

Surgery

Malignancy

Thrombophilia

Fractures

COPD

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12
Q

What may an CXR show?

A

Wedge

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13
Q

What may an ecg show?

A

PEA

S1 Q3 T3

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14
Q

What would a d dimer show?

A

Elevated

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15
Q

What would a V/Q show?

A

Mismatch

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16
Q

What is a principle of management>

A

Risk of anticoag therapy V burden of disease.

Eg, alcoholics, COPD and Ca have a high burden but there is a risk of CVAs, peptic ulcer bleeds

17
Q

What is the acute management?

A

O2

Fluids

Analgesia

Clexane and Tpa

18
Q

When would you do a thrombophilia screen?

A

Repeated

Young

FH

PE despite anti coag

Recurrent miscarriages

19
Q

When would you not do a thrombophilia screen?

A

Pregnant

On anticoag therapy

Liver disease

20
Q

What are some thromobophilia diseases that could cause PEs

A

Inherited - Protein C or S deficiency

Factor V leiden

Acquired - LUPUS

Anti phospholipid syndrome

Increased factor 8

21
Q

What is a non drug method for prophylaxis?

A

IVC filter