Thrombocytopenic purpura

Question 1

Occurs at what level of plt

Answer 1

minor trauma/pressure (platelet count < 40,000/μL) or spontaneously (platelet count < 10,000/μL).

Question 2

Caused by what drugs

Answer 2

drugs (cytosine arabinoside, dauno-
rubicin, cyclophosphamide, busulfan, methotrexate, 6-mercaptopurine, vinca alkaloids, thiazide diuretics,ethanol,estrogens

Question 3

Deugs that cause inc plt destruction

Answer 3

drughypersensitivity(sulonamides,

quinine, quinidine, carbamazepine, digitoxin, or methyldopa

Question 4

Skin and mucous findings.

Answer 4

Petechiae—Small (pinpoint to pinhead), red, nonblanching macules that are not palpable and turn brown as they get older, later acquiring a yellowish-green tinge. Ecchymoses—Black-and-bluespots;larger area of hemorrhage.
Vibices—linear hemorrhages, due to trauma or pressure. Most common on legs and upper trunk, but may occur anywhere.
■ Mucous Membranes. Petechiae—Most often on palate and gingival bleeding.

Question 5

management

Answer 5

identify underlying cause and correct, it possible.

Oral glucocorticoids, high-dose IV immunoglobulins,or platelet transfusion for chronicITP(splenectomymaybeindicated>