Leukemia cutis

Question 1

localized or disseminated skin infltration by leukemic cells.It is usually a sign of dissemination of systemic disease or relapse of existing leukemia

Poor prognosis

Answer 1

Leukemic cutis

Question 2

Commonly occurs w what disease

Answer 2

acute monocytic leukemia M5 and acute myelomonocytic leukemia M4.
■ Most commo

Question 3

Skin lesions

Answer 3

Most common lesions are small (2 to 5 mm) papules (Figs. 20-9 and 20-10), nodules (Figs. 20-11 and 20-12), or plaques. LC lesions are usually somewhat more pink, violaceous, or darker than nor- mal skin, always palpable, indurated, and rm.
■ Localized or disseminated; usually on the trunk (Fig. 20-9), extremities (Fig. 20-11), and the ace

Question 4

Treatment

Answer 4

Treatment is directed at leukemia itself.

combination of systemic chemotherapy and local electron beam therapy or PUVA may be necessary or chemotherapy resistant LC lesions.Intralesional chemotherapy has been used in management of localized,single,or a few lesions.