Thrombocytopenia Flashcards

1
Q

What is thrombocytopenia?

A

Is a low platelet count this can be due to production or destruction

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2
Q

Production causing thrombocytopenia?

A

Sepsis
B12 or folic acid deficiency
Liver failure
Leukaemia
Myelodsplastic syndrome

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3
Q

destruction causing thrombocytopenia?

A

Medications
alcohol
immune thrombocytopenia purpra
Thrombotic thrombocytopenia
Heparin induced thrombocytopenia

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4
Q

Diagnosing abnormal bleeding?

A

Thrombocytopenia
Haemophillia A and B
Von willebrand disease
Disseminated intravascular coagulation

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5
Q

What is Immune thrombocytic purpra?

A

This is where antibodies are created against platelets causing an immune response which leads to destruction of platlets.

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6
Q

Management of immune thrombocytic purpra?

A

Predisolone
IV immunoglobins
Rituximab
Splenectomy

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7
Q

What is Thrombocytopenic purpra?

A

This is where there is tiny clots forming in small vessels of body using up platelets and causing thrombocytopenia.

Blood clots form due to problem with ADAMTS13 protein.

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