Lymphoma Flashcards
Definiton of lymphoma?
A group of cancer that affects the lymphatic system and prolifirate within the lymph nodes causing them to become abnormally large
What are Hodgkins lymphoma risk factors?
Hiv
epstein barr virus
Family history
Autoimmune condition like rheumatoid athiritis.
Presentation and symptoms of hodgkins lymphoma?
Enlarged lymph nodes in neck, armpit + groin and will feel rubbery.
Symptoms of hodgkins lymphoma?
Fever
night sweats
weight loss
fatigue
itching
couching
shorthness of breath
abdominal pain
recurrent infection
Investigations for hodgkins lymphoma?
LDH blood test
Lymph node biopsy
Reed steinberg cells
What is ann arbour staging?
Stage 1 = confined to one region of lymph nodes
Stage 2 = More than one region but same side diaphragm
Stage 3 = Affects lymph nodes above and below diaphragm
Stage 4 = widespread involvment
What is Non hodgkins lymphoma?
A group pf different lymphomas a few notable ones:
Burkitt lymphoma
malt lymphoma
Diffuse lymphoma
Risk factors of non hodgkins lymphoma?
HIV
Epstein barr virus
H.pylori
Hepatitis B or C infection
Family history
Exposure to pestocides
Presentations of non hodgkins lymphoma?
same as hodgkins only difference is when biopsied it wont show reed steinberg cells
Managment of Non hodgkins lymphoma?
Waiting
chemotherapy
monoclonal antibodies like rituximab
radiotherapy
stem cell transplantation