Throat- swallowing --> salivary glands Flashcards
4 stages of swallowing
Oral preparatory phase
Oral phase
Pharyngeal (invol, CNIX)
Oesophageal phase
Oral preparatory phase of swallowing
Grinding of control
Oral phase of swallowing
Tongue pushes food bolus towards oropharynx
Pharyngeal phase of swallowing
Soft palate elevates + closes nasopharynx
Pharyngeal constrictor mm contracts from top to bottom, squeezing bolus inferiorly
Oesophageal phase of swallowing
Bolus enters upper oesphageal sphincter
Cricopharyngeus relaxes
Peristalsis - food towards LOS
Dysphagia pattern in malignant lesions
S –> L over w/m
+ W loss
Dysphagia pattern in achalasia/pharyngeal pouch
Slow over years
+ regurg of undigested food
Causes of aspiration (4)
Altered sensation to pharynx centrally
‘’ ‘’ pharynx peripherally (post radiotherapy)
Delays initiation of swallow + food slips in
Neuro/neoplasia –> faults in larynx
What is acute dysphagia usually caused by?
Foreign bodies
If Dysphagia has been occuring for >3 weeks - what investigations should be done?
TNO/FNE
What Ix is good for pharyngeal pouches
Contrast studies
What Ix is good for anatomy + coordination of phases of swallowing
Videofluroscopy
What is Prebysphagia
Decreased ability to swallow with age
Cause of prebysphagia
Decreased mm mass and strength
PS Prebysphagia (2)
Chronic dysphagia + malnutrition
Aspiration
Tx Presbysphagia (2)
Change consistency of food
Swallowing therapy
Globus pharyngeus
Sensation of lump/tightness in throat w/ no organic cause
Causes globus pharyngeus (2)
Inflamm larynx/hypopharynx
Psychogenic/depression
What is a pharyngeal pouch?
Natural area of weakness in hypopharynx
Posteromedial herniation betw thyropharyngeus + cricopharyngeus
How is a pharyngeal pouch distinguishable on examination?
Large midline lump that gurgles on palpation
Who gets pharyngeal pouches?
Elderly men
Sx pharyngeal pouch (5)
Progressive dysphagia W loss Regurg of undigested food Hallitosis Dysphagia Cough
Tx pharnyngeal pouch
Endoscopic stapling
Swallowing therapy interventions (2)
Head/body posture
Control of bolus flow
Supraglottis
Above vocal chords
Including epiglottis + false VC
Inn supraglottis
Superior laryngeal nn
Glottis
True VC
Subglottis
From VC to trachea
Inn subglottis
Recurrent larygneal nn
Changes in vocal cords: Incr mass –>
Decr pitch of voice
Changes in vocal cords: Poor closure –>
Weak voice
Changes in vocal cords: Incr stiffness
Rough voice
Changes in vocal cords: Lesions on free edge
Irregular voice + breaking
How are the vocal cords examined?
FNE
How long does acute laryngitis last?
2 w
Tx acute laryngitis (4)
Fl
Analgesia
Anti-inflamm Dx
Avoid using voice
RF Chronic Laryngitis
Smoking
Alcohol
Excessive use of voice
Mx Chronic Laryngitis (2)
SALT
Avoid RF
What can chronic laryngitis progress into?
Carcinoma
Causes of VC palsy (2)
Recurrent laryngeal nn
Trauma
Mediastinal mass/thyroid malig
Cause of vocal cord nodules
Recurrent trauma to edge VC
B/c XS voice production
Mx vocal cord nodules (2)
SALT
Rest voice
What is mm tension dysphonia?
Inco-ordination of laryngeal mm
Ix for all changes in voice
CXR/FNE
Red flags for voice (SCALD)
S- Smoker/stridor C - Consistent/cough blood A - Acute onset not related to URTI L - Loss of W D - Dyspnoea + dysphagia
The 3 groups of Voice Treatment
Voice therapy
Medical therapy
Surgical therapy
Voice therapy (4)
Vocal hygiene
Lubrication
Hydration
Advice on caffiene/alcohol
Medical therapy voice (3)
ABx
Anti-reflux meds
Botox for spasmodic dysphonia
Surgical therapy for voice
Endolaryngeal surgery w/ laser
Which major salivary gland are most of the tumours in?
Parotid
Is Parotid mucous or serous
Serous
Name of Parotid duct
Stenson’s duct
Where does Stenson’s duct enter the mouth?
Level of 2nd upper molar
Which major salivary gland are most of the stones formed?
Submandibular gland
Is Submandibular gland mucous or serous?
Both
Name of Submandibular duct
Whartons
Where does Whartons duct enter the mouth
Either size of frenulum
Where is the sublingual gland?
Lines the floor of the mouth
Is the sublingual gland mucous or serous?
Mucous
Salivary stimuli (5)
Smell Taste Psychic stimuli Chewing/mastication Parasymp Dx - pilocarpine
Xerostomia
Dry mouth
Common causes of Xerostomia (6)
Depression Anxiety Drugs with antimuscarinic activity Drugs with sympathomimetic activity Sjorgren's syndrome Radiothearpy H+N region
Drugs with antimuscarinic properties that can cause xerostomia (7)
Atropine Ipratropium TCAs MOAIs Phenothiazines Anti-parkinson drugs AntiH
Drugs with sympathomimetic activity that can cause xerostomia (3)
Cold cures/decongestants
Bronchodilators
Appetite suppressants
What is the most common cause of bilateral parotid enlargement?
Mumps
Other causes of parotitis (apart from mumps) (4)
HIV
Bacterial - staphy
Fungal
Sarcoid
Sialadenitis
Acute infection of partoid/SM gland
Sx Sialadenitis (6)
Pain Pyrexua Swollen glands Pus @ opening parotid ducts --> bad taste SM - swollen floor of mouth Less saliva
Who gets Sialadenitis?
Old patients w/ poor dental hygiene
Tx Sialadenitis (3)
High dose ABx
Rehydration
Oral care
Sialoithiasis
Formation of stones in salivary glands
Which gland does Sialolithiasis tend to occur?
SM glands
S+S Sialolithiasis (4)
Colicky pain
Postprandial swelling
Gland swollen
Gland tender
Tx Sialolithiasis (2)
Fl
Sialogues
1’ Sjorgens syndrome
Dry eyes + dry mouth
2’ Sjorgens syndrome
Dry eyes + Dry mouth
CT disease
3 + 4 Sjorgens
3 = Benign lymphoepithelial lesion 4 = Aggressive lymphocytic behaviour confined to parotid glands
Sx Sjorgens (4)
Dry eyes
Keratoconjunctivitis
Chronic hepatitis
Vasculitis
Why does Sjorgen’s syndrome occur?
Loss of suppressor T cell activity
Ix Sjorgens syndrome (3)
HLA/AI/DR3
Specific antigens - SSB/SSA
Labial biopsy = diagnostic
Risks of having Sjorgens syndrome
1/6 –> Non-Hodgkins B cell lymphoma
Tx Sjorgens (2)
Steroids
Artificial tears, saliva, lubricants
Where are the majority of benign salivary gland tumours found?
Parotid gland
Which salivary glands has the highest % of being malignant?
Minor salivary glands
RF Benign salivary gland tumours
Previous radiation
What is the most common type of benign salivary gland tumour?
Pleomorphic adenoma
Where do you tend to find pleomorphic adenomas?
Parotid gland
Can pleomorphic adenomas become malignant?
Yes, over many years (only 10%)
Ix Pleomorphic adenoma
FNAC/CT
Tx Pleomorphic adenoma
Surgical excision
Where are Warthins tumours found
Partoid tails bilaterally
Who gets Warthin’s tumours
Old men
Tx Warthins tumours
Surgical excision
How do malignancies in the salivaries glands present? (3)
Rapid growing
Painful
Involving other structures e.g. facial palsies
Features of high grade muco-epidermoid tumours
Painful
Fully invasive
Rapid growth
Mets for mucoepidermoid tumours (4)
Lungs
Brain
Bone
Local lymph
Which gland is the majorty of muco-epidermoid tumours in?
Parotid
Tx low grade muco-epidermoid tumour
Local resection
Tx - high grade muco-epidermoid tumour
Radical neck dissection + radiotherapy
Prognosis Muco-epidermoid tumours
30% recurrence :(
Where are 99% of Acini cell tumours?
Parotid gland
Tx Acini cell tumours
Resection
Preserve CN 7
What is the most common salivary gland malignancy?
Adenoid cyst carcinoma
How does Adenoid cyst carcinoma spread?
Gradually
Invading extensively w/ infiltration along nn
Tx Adenoid cyst carcinoma
Radical excision
Radiotherapy
Prognosis Adenoid cyst carcinoma
15%
What is the most common type of lymphoma in salivary glands?
Non-Hodgkin’s lymphoma
PS lymphoma in salivary glands (3)
Firm mass
Rapidly enlarging
Occasional LN met s
How would you diagnose a lymphoma/
Biopsy
Tx - Malignant salivary gland tumours
Partial superficial parotidectomy
Submandibular gland excision