Thinner Reversal Flashcards
What is the mechanism of and
approach to reversal of
clopidogrel?
Anti-platelet agent monitored with P2Y12 level
can cause hemorrhage, TTP, neutropenia.
Tx with platelet transfusion.
What is the drug of choice to reverse dabigatran?
Idarucizumab.
_______________ is a monoclonal antibody fragment that is used to reverse the direct oral anticoagulant dabigatran
Idarucizumab
____________ is the reversal agent for heparin.
Protamine sulfate
________________ is the preferred reversal agent for life-threatening bleeding in patients on warfarin.
Prothrombin complex concentrate
Hemophilia A patients with major or life-threatening bleeding should be given _______ of factor VIII.
50 IU/kg of factor VIII