Things to remember

Question 1

What is the substrate for phosphodiesterase?

Answer 1

cAMP

Question 2

Do ketone bodies form in the fasting or well fed state?

Answer 2

fasting

Question 3

glycerol digestions only occurs where?

Answer 3

hepatocytes

Question 4

what enzyme for ketone bodies is absent in hepatocytes?

Answer 4

B-ketoacyl CoA transferase

Question 5

What enzyme in the CAC has the same mechanism as PDH?

Answer 5

a-ketogluterate DH

Question 6

What are the inhibitors of Complex I?

Answer 6

Rotenone
amytal

Question 7

What is the inhibitor of Complex II?

Answer 7

TTC

Question 8

What are the inhibitors of Complex III?

Answer 8

myxothiazol
antimycin A
stigmatellin

Question 9

What are the 4 coupling agents?

Answer 9

1. 2, 4-dinitrophenol
2. fluorocarbonyl CP
3. dicoumarol
4. thermognin (brown fat)

Question 10

CoA
Transient or prosthetic
what subunit?

Answer 10

E1
transient

Question 11

TPP
Transient or prosthetic
what subunit?

Answer 11

E2
prosthetic

Question 12

lipoamide
Transient or prosthetic
what subunit?

Answer 12

E2
prosthetic

Question 13

FAD
Transient or prosthetic
what subunit?

Answer 13

E3
prosthetic

Question 14

NAD
Transient or prosthetic
what subunit?

Answer 14

E3
transient

Question 15

What cofactor creates trans double bonds?

Answer 15

FAD

Question 16

What cofactor always has H2O involved?

Answer 16

NAD

Question 17

what cofactor adds S-CoA?

Answer 17

lipoamide

Question 18

What is the order of FA synthase?

Answer 18

1. KS
2. MAT
3. KS
4. KR
5. DH
6. ER

Question 19

What is the order of molecules in B oxidation?

Answer 19

1. Acyl CoA (DH) ((FADH2))
2. Trans Enoyl CoA (hydratase)
3. L-B- hydroxacyl CoA (DH) ((NADH))
4. B-ketoacyl CoA (thiolase)

Question 20

What is the commitment step in CAC?

Answer 20

isocitrate DH

Question 21

What is the membrane bound enzyme in CAC?

Answer 21

succinate

Question 22

what CAC enzyme is catalytic perfection?

Answer 22

fumarase