Thin Teenager Flashcards

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1
Q

What are the risks of rapid weight loss?

A
  • Refeeding syndrome risk (metabolic disturbances occurring due to re-nourishing starved patients)
  • Hypoglycaemia
  • Risk of infection
  • Cardiac arrhythmia
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2
Q

What are investigations to be done in a thin teenager?

A
  • Height and weight
  • HR
  • Temperature
  • Lying and standing BP
  • BM
  • RR
  • CRT
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3
Q

What would a history of rapid weight loss include?

A
  • Abdominal pain, malaena, diarrhoea, joint pains, bloating, fever
  • Body image: ‘feeling fat’, preoccupation with calories, won’t eat, vegan, exercising, perfectionist shape, clothes now loose, new clothes size
  • FH of eating disorder, FH of major mental illness
  • Drugs/alcohol in family
  • Menstrual hx, vomiting, binging, laxative use, amount being eaten and drunk, hiding food, excess exercise, safeguarding issues
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4
Q

What conditions can cause rapid weight loss in adolescents?

A
  • Coeliac disease
  • T1DM
  • Hyperthyroidism
  • Malignancy
  • Anorexia nervosa
  • IBD
  • Oesophageal problems e.g. achalasia
  • Severe depression/OCD/autism
  • Juvenile arthritis
  • Addison’s disease
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5
Q

What test might you do in extreme/sudden weight loss?

A
  • ECG
  • U+E, BM, phosphate, Ca, Mg
  • LFTs
  • CRP, ESR, WCC
  • TFTs
  • Anti-TTG
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6
Q

What does emaciated mean?

A

Abnormally thin or weak, especially because of illness or lack of food

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7
Q

What is the management for a starved individual?

A
  • Admit to stabilise physically
  • Commence vitamins (thiamine, vit B complex, multivitamins) to prevent refeeding syndrome
  • Regular obs and BM
  • Monitor bloods
  • Contact local eating disorders team - diet plan
  • IV fluids if hypoglycaemic or not drinking (10% dextrose and 0.45% saline)
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8
Q

When is someone at risk of refeeding syndrome?

A

If weight to height ratio <75% then need to give vitamins. Children who are starved will adapt by reducing their metabolic state and are at risk of metabolic decompensation when being refed.

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9
Q

What is lanugo hair?

A

Hair growth e.g. on cheeks - response to loss of insulating effect of fat tissue

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10
Q

What other blood test results can present in a thin teenager?

A
  • Likely dehydration if not drinking
  • Decreased WCC could represent haematological malignancy, however decreased WCC can be seen with weight loss - obtain blood film
  • Liver abnormality can be caused by weight loss due to depletion of glycogen - test for glandular fever, Hep A, B and C, coagulation screen and liver USS
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11
Q

What is the short term (physical stabilisation) treatment for anorexia nervosa?

A
  • Weight for height ratio <75% - commence thiamine, vit B complex and multivitamins
  • Diet plan: aim for 0.5-1kg per week weight gain. An initial drop in weight may be noted as body leaves starvation mode.
  • Monitor bloods (especially phosphate)
  • Regular ECGs
  • Discharge when vital signs stable and weight gain occurring, discuss with ED team regarding discharge and treatment plan.
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12
Q

What do you monitor in case of refeeding syndrome?

A

Phosphate - drop in phosphate is a marker of refeeding syndrome and may precipitate respiratory arrest (increased food uptake triggers protein/fat/glycogen synthesis, which require phosphate, K and magnesium). These are already depleted but decrease further upon refeeding.

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13
Q

What is beriberi?

A

Inflammation of nerves and HF, due to B1 deficiency (thiamine)

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14
Q

What is the medium term treatment for anorexia nervosa?

A

MDT treatment package in community:

  • Child psychiatrist diagnoses and oversees care
  • Prescribes medication
  • Directed treatment for co-morbidities e.g. fluoextine for OCD
  • Dietician gradually increasing diet plan to be agreed and adhered to
  • Avoid supplements - patients need to learn to eat
  • Therapists (often nurses) work on changing thought processes - takes time
  • Family therapist looks at family dynamics - very stressful disease - different personalities have varying abilities to cope
  • Paediatrician monitors physical health
  • Concern re long-term risk of osteopenia and osteoporosis especially in young ladies with amenorrhoea. Role of DEXA scan for monitoring BMD.
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15
Q

What is the long term relapse prevention for anorexia nervosa?

A
  • Transition phases e.g. going to univeristy
  • Long-term outlook - 80% cure
  • 3rd sector e.g. BEAT charity
  • Risk of severe enduring eating disorder
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16
Q

What is the aetiology of anorexia nervosa?

A

A neuro-biological illness:

  • Genetic factors (FH of AN or other major mental illness important)
  • Events around puberty
  • Cultural promotion of thinness (least important)
17
Q

What are the 3 main types of eating disorder in young people?

A
  • Anorexia nervosa
  • Bulimia nervosa
  • EDNOS (eating disorder not otherwise specified)
18
Q

What are the key features of anorexia nervosa?

A
  • Reducing calories enough to cause significant weight loss
  • Intense fear of gaining weight or becoming fat
  • Distorted perception of body image (thinking they are fat when they are very skinny)
19
Q

What are the key features of bulimia nervosa?

A
  • Binge eating (lack of control over amount they eat)
  • Intentional vomiting, self-harm (might be of normal weight)
  • Low self-worth, often co-morbid with other forms of self-harm e.g. cutting
  • Poor dentition, often glucose intolerance
20
Q

What are the key features of EDNOS?

A
  • Outlook better than pure anorexia nervosa

- Fulfils some but not all features of anorexia nervosa

21
Q

What are the behavioural/psychological features of AN?

A
  • Pre-occupation with food
  • Feeling fat - unhappy with body
  • Won’t eat in front of others
  • Hiding food
  • May be compulsive exerciser
22
Q

What are the clinical features of AN?

A
  • Low weight for height
  • Amenorrhoea
  • Headaches
  • Cool peripheries
  • Bradycardia, palpitations
  • Hypotension
  • Constipation
  • Dry skin, hair loss/thinning/brittle
  • Fainting/dizziness
  • Lethargy/tiredness - anaemia
  • Peripheral oedema
  • Hypothermia
23
Q

What are common co-morbidities with ED?

A
  • OCD

- Depression

24
Q

What is an accurate way to assess growing young people?

A

Weight for heigh ratio is more accurate than BMI to assess how appropriate their weight is for their height at that age.

25
Q

What are the most significant mortality risks associated with ED?

A
  • Sudden cardiac death
  • Suicide
  • Chronic emaciation and pneumonia
26
Q

What are causes of short stature?

A
  • Familial: beware familial disease e.g. hypochondroplasia
  • Constitutional/delay
  • Psycho-social e.g. unloved upbringing
  • Chronic physical disease
  • Malabsorption - coeliac, Crohn’s
  • Endocrine e.g. hypothyroid, HGH deficiency
  • Genetic/syndromal e.g. Turners
27
Q

What is investigated in a paediatric presenting with short stature?

A
  • General history: diarrhoea, abdo pain, energy
  • Exam: dysmorphic, limb size, skin lesions
  • Parental heights: measure
  • Mid parental centile
  • BP
  • TFTs, U+Es, bone profile, LFTs, CRP, FBC, glucose, anti-TTG
  • Chromosomes - especially in a girl e.g. Turner’s
  • Bone age non-dominant wrist/hand
28
Q

What is normal puberty in girls?

A

First breasts, then pubic hair, then spots/greasy hair and mood changes. Typically menarche starts around 18 months after these changes.

29
Q

What is normal puberty in boys?

A

First testicular enlargement (orchidometer), then genital changes, later pubic hair/voice change

30
Q

What is delayed puberty?

A

If there is no sign age 14 in boys or 13 in girls

  • Beware brain tumour
  • Often borderline delayed puberty associated with a pause in growth
31
Q

What is precocious puberty?

A
  • Signs of puberty before 8 in a girl or 9 in a boy
  • More likely to be pathological e.g. craniopharyngioma in boy/girl <6yrs
  • Girl >6.5 usually idiopathic central precocious puberty
  • Psychologically distressing and may compromise final height - will offer blockade with GNRH antagonist e.g. Zoladex (injection)
32
Q

What thyroid disorders occur in young people?

A
  • Congenital hypothyroid
  • Cretin - severe learning difficulty develops if not treated
  • Acquired hypothyroid - teenage girls, goitre, autoimmune, +ve TPO antibodies