Thiazide + Thiazide-like Diuretics Flashcards
1
Q
Examples
A
Bendroflumethiazide
Chlortalidone
Indapamide
2
Q
Mode of action
A
Thiazide sensitive Na/Cl co-transporter in DCT
Inhibitor
Reduces Na+ and Cl- reabsorption
Removal of salt, vasodilator action
3
Q
Indications
A
Hypertension
Oedema
4
Q
Adverse drug reactions
A
Oto + Nephrotoxicity Hypotension Hyponatraemia/kalaemia Hypercalcaema Increase pH and urea AKI Dehydration Hyperglyceamia
5
Q
Prescribing Advice
A
eGFR >30
X w/ Aminoglycoside, NSAIDs, Lithium, SSRI