Thiazide + Thiazide-like Diuretics Flashcards

1
Q

Examples

A

Bendroflumethiazide
Chlortalidone
Indapamide

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2
Q

MoA

A

Thiazide sensitive Na/Cl co-transporter in DCT
Inhibitor
Reduces Na+ and Cl- reabsorption
Removal of salt, vasodilator action

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3
Q

Indications

A

HTN (3rd line)

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4
Q

ADR

A
Oto + Nephrotoxicity
Hypotension
Hyponatraemia/kalaemia
Hypercalcaema
Increase pH and urea
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5
Q

Prescribing Advice

A

eGFR >30

X w/ Aminoglycoside, NSAIDs, Lithium, SSRI

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