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Diuretics > K+ Sparing (Aldosterone - Dependent) > Flashcards

K+ Sparing (Aldosterone - Dependent) Flashcards

1
Q

Examples

A

Spironolactone

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2
Q

MoA

A

Intracellular aldosterone mineralocorticosteroid receptor in DCT
Antagonist
Prevent action of aldosterone
Reduces fluid retention and Vasoconstriction

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3
Q

Indications

A

Aldosteronism
Liver Ascites
Resistant HTN

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4
Q

ADR

A 
Oto and Nephrotoxicity
Hypotension
Hyperkalaemia
Hyponatraemia
Sexual dysfunction
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5
Q

Prescribing Advice

A

X w/ ACEi, ARBs, Beta-Blockers, NSAIDs

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Diuretics (4 decks)

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