Loop Diuretics Flashcards

1
Q

Examples

A

Furosemide

Bumetanide

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2
Q

MoA

A

NA+/K+/2Cl- co-transporter in LoH
Inhibitor
Reduces Na+, K+, Cl- reabsorption
Most powerful diuretic = Excretion of 15-25% filtered Na+

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3
Q

Indications

A

Oedema

Congestive Heart Failure

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4
Q

ADR

A
Oto + Nephrotoxicity
Hypotension
Hyponatraemia/kalaemia
Hypercalcaemia
Increase pH and Urea
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5
Q

PRESCRIBING ADVICE

A

X w/ Aminoglycosides or NSAIDs

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