Thermo set 2 (1)

Question 1

What is the ΔG of H transfer during ATP synthase?

Answer 1

-movement of ions from high to low conc.
-pushed by excess H+ on 1 side (electrostatic)
- -ive

Question 2

What is ΔG of ADP + Pi –> ATP during ATP synthase?

Answer 2

-trying to increase ATP conc.
-in conditions where natural tendency is to decrease ATP conc.
- +ive

Question 3

How do you calculate the overall ΔG for ATP synthase?

Answer 3

ΔG H transfer + ΔG ADP + Pi –> ATP

Question 4

What is the entropy of mixing and why?

Answer 4

-low entropy at start - small no. of states
-high entropy when mixed - large no. of states
-at start - all microstates are equally likely + randomly positioned, so it’s ordered
-when mixed - spontaneous, has a greater number of possible arrangements

Question 5

How do you calculate the ΔG for the whole system when transferring 1 molecule from a to b?

Answer 5

ΔG = Kb x T x ln (Cb/Ca)

Question 6

How do you calculate the ΔG when transferring 1 mole from a to b?

Answer 6

ΔG = RT x ln(Cb/Ca)

Question 7

Is the equilibrium constant fixed or does it vary?

Answer 7

A fixed number for a particular reaction

Question 8

Is the mass action ratio a fixed number or does it vary?

Answer 8

-varies
-depends on the actual concentrations