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CC-review > therapeutic drug monitoring > Flashcards

therapeutic drug monitoring Flashcards

1
Q

specimen for TDM

A

SERUM (commonly used)
plasma
whole blood

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2
Q

Cardioactive Drugs

A 
Digoxin
Procainamide
Lidocane (xylocane)
Quinidine
Disopyramide
Propanolol
Amiodarone
Verapamil
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3
Q

alters cardiac ions cardioactive drug

A

Digoxin

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4
Q

lowers BP & cardiac output cardioactive drug

A

Lidocane (xylocane)

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5
Q

blood dyscrasia cardioactive drug

A

Quinidine

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6
Q

lupus-like syndrome cardioactive drug

A

Procainamide

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7
Q

Antibiotics

A

Aminoglycosides
Vancomycin
Chloramphenicol

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8
Q

Antibiotic that is for Gram (-) ; protein synthesis inhibitors, and assoc. w/ blood dyscrasia

A

Chloramphenicol

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9
Q

cell wall inhibitor, againstGram (+) , nephro-&ototoxicity

A

Vancomycin

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10
Q

“red man syndrome”

A

Vancomycin

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11
Q

Antiepileptic drugs

A 
Phenytoin
Valproic acid
Carbamazepine
Ethosuximide (Zantin)
Neurontin (Gabapentin)
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12
Q

nystagmus

A

Neurontin (Gabapentin)

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13
Q

pancreatitis

A

Valproic acid

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14
Q

initiation of seizure

A

Phenytoin

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15
Q

Bronchodilator

A

Theophylline

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16
Q

Immunosuppressor

A

Cyclosporin
Tacrolimus
Rapamycin

17
Q

Immunosuppressor drug testing specimen

A

Whole blood EDTA

18
Q

Antineoplastic/Anticancer

A

Methotroxate

Busulfan

19
Q

Anti-inflammatory

A

Salicylates/Aspirin

Acetaminophen

20
Q

Neuroleptics

A

Risperdal
Olonszapine
Quetapine
Asopiprazole

21
Q

Reference method for TDM

A

GC-MS

22
Q

what must be avoided in sample collection for TDM specimen

A

Serum Separator Tube (Nixothropic gel)

23
Q

single most important factor in TDM

A

Timing of specimen collection

24
Q

Through concentration

A

blood must be collected 30 mins/immediately before next dose

25
Q

Peak concentration

A

blood drawn an hour after oral dose

CC-review (6 decks)

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