Therapeutic Antibodies Flashcards

1
Q

Muromonab (OKT3)

A

CD3; prevent acute transplant rejection

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2
Q

Daclizumab

A

IL-2 receptor; prevent acute rejection of kidney transplant

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3
Q

Digoxin Immune Fab

A

digoxin; antidote for digoxin toxicity

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4
Q

infliximab

A

TNFa; crohn’s disease, RA, psoriatic arthritis, ankylosing spondylitis

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5
Q

Etanercept

A

TNFa; crohn’s disease, RA, psoriatic arthritis, ankylosing spondylitis

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6
Q

Adalimumab

A

TNFa; crohn’s disease, RA, psoriatic arthritis, ankylosing spondylitis

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7
Q

Abciximab

A

glycoprotein 2b/3a; prevent cardiac ischemia in unstable angina and in patients treated with percutaneous coronary intervention

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8
Q

Trastuzumab

A

erb-B2; Her2 overexpressing breast cancer

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9
Q

Rituximab

A

CD20; B cell non-Hodgkin’s lymphoma

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10
Q

Omalizumab

A

IgE; severe asthma

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11
Q

Imatinib

A

bcr-abl tyrosine kinase; chronic myelogenous leukemia

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