Therapeutic Antibodies Flashcards
Muromonab (OKT3)
CD3; prevent acute transplant rejection
Daclizumab
IL-2 receptor; prevent acute rejection of kidney transplant
Digoxin Immune Fab
digoxin; antidote for digoxin toxicity
infliximab
TNFa; crohn’s disease, RA, psoriatic arthritis, ankylosing spondylitis
Etanercept
TNFa; crohn’s disease, RA, psoriatic arthritis, ankylosing spondylitis
Adalimumab
TNFa; crohn’s disease, RA, psoriatic arthritis, ankylosing spondylitis
Abciximab
glycoprotein 2b/3a; prevent cardiac ischemia in unstable angina and in patients treated with percutaneous coronary intervention
Trastuzumab
erb-B2; Her2 overexpressing breast cancer
Rituximab
CD20; B cell non-Hodgkin’s lymphoma
Omalizumab
IgE; severe asthma
Imatinib
bcr-abl tyrosine kinase; chronic myelogenous leukemia