Chromosomal Translocations Flashcards by Payal Patel | Brainscape

Q

Chronic myelogenous leukemia

A

t(9;22) — bcr-abl tyrosine kinase

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Q

Burkitt’s lymphoma

A

t(8;14) — c-myc activation

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Q

Follicular lymphoma

A

t(14;18) — bcl-2 activation

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Q

Acute promyelocytic leukemia

A

t(15;17) — retinoic acid receptor disruption

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Q

Ewing’s sarcoma

A

t(11;22)

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Q

Mantle cell lymphoma

A

t(11;14) — cyclin D1 overexpression

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Q

Acute lymphocytic leukemia

A

t(12;21)

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