Autoantibodies Flashcards

1
Q

antinuclear

A

SLE, nonspecfic

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2
Q

anti-dsDNA, anti-Smith

A

SLE (renal disease)

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3
Q

anti histone

A

drug-induced lupus

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4
Q

anti-IgG (rheumatoid factor)

A

rheumatoid arthritis

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5
Q

anti centromere

A

CREST scleroderma

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6
Q

anti-Scl-70 (anti DNA topoisomerase 1)

A

scleroderma (diffuse)

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7
Q

anti mitochondrial

A

primary biliary cirrhosis

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8
Q

anti gliadin, anti endomysial, anti tissue transglutaminase

A

celiac sprue

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9
Q

anti basement membrane

A

goodpasture’s syndrome

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10
Q

anti desmoglein

A

pemphigus vulgaris

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11
Q

anti microsomal. anti thyroglobulin

A

hashimoto’s thyroiditis

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12
Q

Anti-Jo-1

A

polymyositis, dermatomyositis

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13
Q

Anti-SS-A, Anti-SS-B

A

Sjogren’s syndrome

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14
Q

Anti-U1 RNP (ribonucleoprotein)

A

mixed connective tissue disease

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15
Q

anti smooth muscle

A

autoimmune hepatitis

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16
Q

anti glutamate decarboxylase

A

type 1 diabetes mellitus

17
Q

c-ANCA

A

wegener’s granulomatosis

18
Q

p-ANCA

A

microscopic polyangiitis, Chrug-Strauss syndrome

19
Q

Anti-TSH receptor

A

Grave’s disease

20
Q

Anti-ACh receptor

A

Myasthemia gravis

21
Q

MPO-ANCA

A

pauci immune or crescentic glomerulonephritis