(THER) Vasoactive Peptides Flashcards
Captopril MOA and Route
MOA: Ace Inhibitor
Route: Oral
Captopril Indications and Side Effects
Ind: Hypertension
SE: severe stomach pain; chest pain; allergic reaction
Enalapril MOA and Route
MOA: ACE inhibitor
Route: Oral
Enalapril Indications and Side Effects
Ind: Hypertension
SE: Hypotension; severe stomach pain
Losartan MOA and Route
MOA: Angiotensin receptor inhibitor
Route: Oral
Losartan Indications and Side Effects
Ind: Hypertension
SE: Diarrhea; insomnia; nasal congestion
Valsartan MOA and Route
MOA: Angiotensin receptor inhibitor
Route: Oral
Valsartan Indications and Side Effects
Ind: Hypertension
SE: Stomach pain; nausea
Icatibant MOA and Route
MOA: Bradykinin receptor inhibitor
Route: Oral
Icatibant Indications and Side Effects
Ind: Inflammation
SE: stomach pain; nausea
Desmopressin (DDAVP) MOA and Route
MOA: Vasopressin analogue; Increases the factor VIII activity of patients with mild hemophilia and VWD.
Route: IV
Desmopressin Indications and Side Effects
Ind: Bleeding (Initially developed for Pt. w/ diabetes insipidus)
SE: Headache; stomach pain; nausea
Bosentan MOA and Route
MOA: Endothelin receptor inhibitor
Route: Oral/ IV
Bosentan Indications and Side Effects
Ind: Pulmonary arterial hypertension
SE: Liver problems; stomach pain; nausea
Name the (3) most important vasoactive peptides
- Angiotensins (I, II and III)
- Bradykinin/related kinins
- Endothelins
Which of the angiotensins is the active form ( I, II, or III?)
Angiotensin II is the only active form and produces profound vasoconstriction and other pharmacologic responses