Theme 4A Flashcards

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1
Q

what is the problematic theories from mid 1800s…
what is blending inheritance?

A

offspring have traits that are intermediate to their parents
ex. child and parents you can see parts of both parents in the children

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2
Q

what is the problematic theories from mid 1800s…

what is the theory from lamarck?

A

” inheritance of acquired traits” in other words, favourable traits acquired by parents are passed on to offspring
-directed evolution

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3
Q

if blending inheritance is the mechanism what do we tend to see?

A

if blending inheritance was the mechanism variation will be reduced over time
- does not reflect the constant presence of variation observed in populations
-looks at individual as a whole doesn’t look at individual traits

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4
Q

who is gregor mendel and what did he test?

A
  • how did offspring pick up traits of inheritance
    tested hypothesis of blending vs.particulate inheritance
  • used true-breeding varieties of peas
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5
Q

what are the certain traits mendel looked for in the peas?

A

seed colour
seed shape
pod colour
pod shape
flower colour
flower position
plant type

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6
Q

what was mendel trying to achieve?

A

determine whether statistical patterns in the occurrence of the contrasting traits persisted by means of crossing

1) true breeding strains (“good” phenotypes) make sure when breeding same type came out
2) focusing on single trait at a time
3) Quantitative: counted the progeny

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7
Q

what are two generations called in reciprocal F1 crosses?

A

Parent generation
(P1)

(F1) First Filial generation

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8
Q

What are some key aspects that determine the difference between dominant versus recessive?

A

Often the dominant allele codes for a functional protein whereas the recessive allele does not.
-pea colour is determined by the presence of a functional enzyme that breaks down chlorophyll

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9
Q

parental generation always start with true breeding? TRUE OR FALSE

A

TRUE

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10
Q

what is considered a good symbol?

A

mutation a mutant allele/phenotype or recessive phenotype (usually rare phenotype)
ex. Gg

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11
Q

what is segregation of alleles, and explain the single character (monohybird) cross?

A

There is a parental generation: cross two true-breeding varieties with a different phenotype

F1 generation seeds (Filial) : F1 “self-fertilize”

F2 generation seeds: the parental generation appeared again.
goes against blending inheritance. Mendel saw green plants come back.
- clear ratio to 3:1

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12
Q

what did mendel propose from segregation experiment?

A

Principle of segregation tested by predicting the outcome of crosses
- the expected ratio of dominant to recessive phenotype is 3:1 phenotype ratio

  • Expected genotypic ratio.
    A/A:A/a/aa
    1:2:1
  • 1 homozygous dominant
  • 2 heterozygotes
  • 1 homozygous recessive
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13
Q

the punnet square makes two strong predictions what are they?

A

-seeds in the F2 generation showing the recessive green phenotype should be homozygous recessive a/a.
- the A/A and A/a genotypes: distinguished by seeds produced when F1 is self-fertilized

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14
Q

What was mendels hypothesis of particulate inheritance?

A
  • all adult plants replicate through sexual reproduction carry two factors that contribute to the phenotype or inheritance character (ex. wrinkled vs smooth)
  • if individual pair of genes consists of different alleles, one dominant over the other.
  • Mendel ideas to meiosis:
    pair of alleles that separate in formation of gametes.
    so in case of mendel we have these 2 copies of these factors, and for every sperm or egg that is produced from these plants gonna get one of these 2 factors:
  • half gametes (haploids) have big A half have little a
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15
Q

what is mendels principle of segregation?

A

idea that in a deployed organism each gammy is going to get one allele from each parent

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16
Q

what is a monohybrid cross?

A

a cross between two heterozygotes (for a single gene)

17
Q

what are some key concepts we need to know about monohybrid crosses?

A

-probability of a gamete inheriting one of the two alleles during meiosis is random (random alignment of chromosomes at the metaphase plate)

18
Q

what is a test cross?

A

to determine whether the dominant phenotype is a homozygote or heterozygote
- procedure: cross individual with dominant phenotype to a homozygous recessive

  • if heterozygous (P/p) then see 1:1 of dominant and recessive phenotypes
  • if homozygous (P/P), then see all dominant phenotype

ex. Aa x aa

19
Q

what does segregation of alleles reflect?

A

the separation of homologous chromosomes during anaphase I of meiosis.

20
Q

what is the mendels chromosomal theory of inheritance?

A

idea that all of these alleles, all these traits exist on chromosomes and get separated from each other during meiosis

21
Q

explain what alleles and genes are, and how their expression results in different phenotypes?

A

Genes are segments of DNA that provide instructions for building proteins, which carry out various functions in the body. Alleles are different versions of a gene that can exist. Each person inherits two alleles for each gene, one from each parent.

The combination of alleles determines how a gene is expressed, leading to different traits or phenotypes. For example, a gene for eye color might have an allele for blue eyes and an allele for brown eyes. The specific alleles someone has will determine their eye color phenotype.

22
Q

Explain how meiosis determines the frequency and genotype of gametes of homozygous and heterozygous individuals

A

Meiosis is the process that creates gametes (sperm and egg cells) with half the number of chromosomes of normal cells. For a homozygous individual (with two identical alleles, like AA or aa), all gametes will receive the same allele (either A or a).

For a heterozygous individual (with two different alleles, like Aa), meiosis produces gametes with equal frequency of each allele. Half of the gametes will have the A allele, and the other half will have the a allele. This random separation of alleles ensures genetic diversity in offspring.

23
Q

Explain mendels genetic crosses (monohybrid and test cross) and the associated genotypic and phenotypic ratios.

A

Monohybrid Cross:

A monohybrid cross involves one trait.
For example, crossing two heterozygous individuals (Aa x Aa).
Genotypic ratio: 1 AA : 2 Aa : 1 aa.
Phenotypic ratio: 3 dominant (A) : 1 recessive (a).
Test Cross:

A test cross determines the genotype of an individual with a dominant phenotype.
Cross the individual with a homozygous recessive (aa).
If the unknown genotype is AA, all offspring will show the dominant trait.
If the unknown genotype is Aa, the offspring will have a 1:1 ratio of dominant to recessive traits.

24
Q

explain the difference between incomplete dominance and co-dominance and how these affect phenotypic ratios.

A

incomplete Dominance:

Neither allele is completely dominant.
Heterozygous phenotype is a blend of both alleles.
Example: Red (RR) x White (rr) flowers produce Pink (Rr) flowers.
Phenotypic ratio: 1 red : 2 pink : 1 white.
Codominance:

Both alleles are fully expressed in the heterozygous state.
Example: Black (BB) x White (WW) chickens produce speckled black and white (BW) chickens.
Phenotypic ratio: 1 black : 2 speckled : 1 white.
In incomplete dominance, the heterozygous phenotype is a mix, while in codominance, both traits appear simultaneously.

25
Q

what is polymorphic?

A

Refers to the presence of two or more different forms or alleles of a gene in a population.
Example: Blood types A, B, AB, and O are polymorphic traits in humans.

26
Q

what is a discrete trait?

A

Discrete Trait:

A trait that has distinct and separate forms or categories.
Example: Pea plant flower color being either purple or white.

27
Q

what are complex traits or polygenic traits?

A

Complex Traits (Polygenic Traits):

Traits influenced by multiple genes.
Often also affected by environmental factors.
Example: Height, skin color, and intelligence.