The vascular system and blood Flashcards

1
Q

What are the main plasma proteins?

A
  • Albumin
  • Globulin
  • Fibrinogen
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2
Q

What are the main cells found in the bood?

A
  1. Erythrocytes (red blood cells)
  2. Leukocytes (white blood cells)
  3. Platelets
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3
Q

What is the diameter of a red blood cell?

A

~7 µm

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4
Q

What is the lifespan of a red blood cell?

A

120 days

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5
Q

What are platelets derived from?

A

Megakaryocytes

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6
Q

What is the lifespan of a platelet?

A

10 days

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7
Q

What are the 2 categories of white blood cells?

A
  1. Granuocytes
  2. Agranulocytes
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8
Q

What are the types of granulocytes?

A
  1. Neutrophils
  2. Eosinophils
  3. Basophils
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9
Q

What are the functions of neutrophils?

A

Ingests and destroys antibody-bound complexes.

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10
Q

What is the relative proportions of different types of white blood cells in the body?

A
  • Neutrophils: 50-60%
  • Eosinophils: 1-2%
  • Basophils: 0-1%
  • Monocytes: 4-8%
  • Lymphocytes: 20-30%
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11
Q

What prominent feature is seen in female neutrophils?

A

Barr body

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12
Q

What are the functions of eosinophils?

A
  • Phagocytosis of bacteria.
  • Killing of phagocytes.
  • Produces substances involved in allergic reactions.
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13
Q

What are the functions of basophils?

A

Systemic anaphylaxis and hypersensitivity during allergic reactions.

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14
Q

What are the types of agranulocytes?

A
  1. Monocytes
  2. Lymphocytes
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15
Q

What are the functions of monocytes?

A
  • Leave the circulation to become macrophages.
  • Involved in engulfing bacteria and cellular debris.
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16
Q

What are the types of lymphocytes?

A
  1. B-lymphocytes
  2. T-lymphocytes
17
Q

What are the layers of a typical blood vessel and their contents?

A
  1. Tunica intima:
    - Endothelium
    - Basement membrane
    - Connective tissue
    - Internal elastic lamina
  2. Tunica media:
    - Smooth muscle
    - Elastin
    - Collagen
    - External elastic lamina
  3. Tunica adventitia:
    - Connective tissue (collagen, elastin)
    - Nerves
    - Vaso vasorum
18
Q

What are the different types of arteries?

A
  1. Elastic artery
  2. Muscular artery
19
Q

What are the key features of arterioles?

A
  1. They have very thin tunica intima.
  2. Intima media contains mainly smooth muscle.
  3. No external elastic lamina.
  4. Tunica adventitia merges with surrounding tissues.
20
Q

What are the key features of veins?

A
  1. They have a much smaller wall:lumen ratio.
  2. They have less well developed tunica media.
  3. No obvious internal elastic lamina.
21
Q

What are the features of venules?

A
  • No tunica media.
  • Thin layer if endothelium lined by some connective tissue.
22
Q

What is the main distinguishing factor between veins and lymphatic vessels?

A
  • Lymphatic vessels lack red blood cells.
  • Presence of precipitated lymph protein.
23
Q

What is the diameter of capillaries?

A

5-8 µm

24
Q

What are the types of capillaries?

A
  1. Continuous capillaries
  2. Fenestrated capillaries
  3. Sinusoidal capillaries
25
Q

What is the lifespan of a neutrophil?

A

1-2 days

26
Q

Where are continuous capillaries commonly found?

A
  • Connective tissue
  • Muscle
  • Lungs
  • Brain
27
Q

Where are fenestrated capillaries commonly found?

A
  • Kidneys
  • Small intestines
  • Endocrine glands
28
Q

Where are sinusoidal capillaries commonly found?

A
  • Liver
  • Spleen
  • Lymphatic tissue
  • Bone marrow
  • Endocrine glands