The vascular system and blood Flashcards
What are the main plasma proteins?
- Albumin
- Globulin
- Fibrinogen
What are the main cells found in the bood?
- Erythrocytes (red blood cells)
- Leukocytes (white blood cells)
- Platelets
What is the diameter of a red blood cell?
~7 µm
What is the lifespan of a red blood cell?
120 days
What are platelets derived from?
Megakaryocytes
What is the lifespan of a platelet?
10 days
What are the 2 categories of white blood cells?
- Granuocytes
- Agranulocytes
What are the types of granulocytes?
- Neutrophils
- Eosinophils
- Basophils
What are the functions of neutrophils?
Ingests and destroys antibody-bound complexes.
What is the relative proportions of different types of white blood cells in the body?
- Neutrophils: 50-60%
- Eosinophils: 1-2%
- Basophils: 0-1%
- Monocytes: 4-8%
- Lymphocytes: 20-30%
What prominent feature is seen in female neutrophils?
Barr body
What are the functions of eosinophils?
- Phagocytosis of bacteria.
- Killing of phagocytes.
- Produces substances involved in allergic reactions.
What are the functions of basophils?
Systemic anaphylaxis and hypersensitivity during allergic reactions.
What are the types of agranulocytes?
- Monocytes
- Lymphocytes
What are the functions of monocytes?
- Leave the circulation to become macrophages.
- Involved in engulfing bacteria and cellular debris.
What are the types of lymphocytes?
- B-lymphocytes
- T-lymphocytes
What are the layers of a typical blood vessel and their contents?
- Tunica intima:
- Endothelium
- Basement membrane
- Connective tissue
- Internal elastic lamina - Tunica media:
- Smooth muscle
- Elastin
- Collagen
- External elastic lamina - Tunica adventitia:
- Connective tissue (collagen, elastin)
- Nerves
- Vaso vasorum
What are the different types of arteries?
- Elastic artery
- Muscular artery
What are the key features of arterioles?
- They have very thin tunica intima.
- Intima media contains mainly smooth muscle.
- No external elastic lamina.
- Tunica adventitia merges with surrounding tissues.
What are the key features of veins?
- They have a much smaller wall:lumen ratio.
- They have less well developed tunica media.
- No obvious internal elastic lamina.
What are the features of venules?
- No tunica media.
- Thin layer if endothelium lined by some connective tissue.
What is the main distinguishing factor between veins and lymphatic vessels?
- Lymphatic vessels lack red blood cells.
- Presence of precipitated lymph protein.
What is the diameter of capillaries?
5-8 µm
What are the types of capillaries?
- Continuous capillaries
- Fenestrated capillaries
- Sinusoidal capillaries
What is the lifespan of a neutrophil?
1-2 days
Where are continuous capillaries commonly found?
- Connective tissue
- Muscle
- Lungs
- Brain
Where are fenestrated capillaries commonly found?
- Kidneys
- Small intestines
- Endocrine glands
Where are sinusoidal capillaries commonly found?
- Liver
- Spleen
- Lymphatic tissue
- Bone marrow
- Endocrine glands