The Urinary System Flashcards

1
Q

What is a congenital anomaly that has a reduced quantity of amniotic fluid, the fetus is compressed by the uterus; this causes low set ears, small receding chin, beak like nose and abnormally bent lower extremities.

A

Potter syndrome

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2
Q

What is the most life-threatening component of Potter syndrome?

A

Pulmonary hypoplasia

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3
Q

What is a congenital anomaly when there is a misplaced kidney(s), due to failure of the fetal kidney to migrate from the pelvis to the flank

A

Renal Ectopia

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4
Q

What is the congenital anomaly called when the kidneys are fused?

A

Horseshoe kidney

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5
Q

What is found at the boundary of the cortex and medulla?

A

Juxtaglomerular apparatus

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6
Q

How much percentage of cardiac output do the kidneys receive?

A

20-30%

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7
Q

What is the equation for normal GFR?

A

GFR = 140 - [your age]

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8
Q

What GFR value is a sign of kidney failure?

A

below 15mL/min

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9
Q

Where can diffusion of water NOT occur in the nephron?

A

Loop of Henle

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10
Q

Is ADH increased or decreased during water deprivation?

A

increased

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11
Q

What condition is characterized by high serum ADH?

A

Syndrome of Inappropriate ADH (SIADH)

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12
Q

What are the 4 structures of a glomerular capillary wall?

A

thin layer of fenestrated endothelial cells
glomerular basement membrane
Podocytes
Mesangium

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13
Q

What type of collagen is the GBM composed of?

A

type 4 collagen

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14
Q

What is Azotemia?

A

decreased Glomerular filtration rate

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15
Q

What is the kidney disorder that causes your body to excrete too much protein in your urine?

A

Nephrotic Syndrome

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16
Q

What are the symptoms of Nephrotic syndrome?

A

proteinuria
hypoalbuminemia
edema
hyperlipidemia

17
Q

What are the symptoms of Nephritic syndrome?

A

hematuria
oliguria
azotemia
hypertension

18
Q

What is a group of kidney diseases characterized by inflammation of the filtering units of the kidney called glomeruli.

A

Glomerulonephritis

19
Q

What happens when the glomeruli are inflamed?

A

they allow passage of protein and blood into the urine

20
Q

What is the most frequent cause of nephrotic syndrome in children leading to loss of too much protein in the urine?

A

Minimal-Change disease

21
Q

What ages are Minimal-Change disease most common in?

A

Ages 1-7

22
Q

What is another name for Minimal-Change disease?

A

Lipoid Nephrosis

23
Q

How do you treat Minimal-Change disease?

A

corticosteroids

24
Q

What condition is characterized by sclerosis affecting some but not all glomeruli

A

Focal Segmental glomerulosclerosis (FSGS)

25
Q

What race is FSGS the primary leading cause of Nephrotic syndrome?

A

African Americans

26
Q

What is Stage 1 of Membranous Nephropathy (Membranous Glomerulonephritis)?

A

no projections of GBM material

27
Q

What is Stage 2 of Membranous Nephropathy (Membranous Glomerulonephritis)?

A

projections of GBM material around immune complexes

28
Q

What is stage 3 of Membranous Nephropathy (Membranous Glomerulonephritis)?

A

enclosure of immune complexes around GBM

29
Q

What is Stage 4 of Membranous Nephropathy (Membranous Glomerulonephritis)?

A

thickened GBM

30
Q

What race is Membranous Nephropathy the primary leading cause of Nephrotic Syndrome?

A

White and asian