The synapse Flashcards
the perpetuation of the nerve impulse from one neuron to the next cell is called
synaptic transmission
the junction between two neurons or a neuron and target cell
synapse
In the synapse, the physical gap between two nerve cell
synaptic cleft
the neuron bringing the nerve impulse to the synapse and releasing the chemical to stimulate the next cell
presynaptic neuron
chemical released by the presynaptic neuron
neurotransmitter
the neuron that contains the receptors that receive the neurotransmitter
postsynaptic neuron
what do synaptic knobs contain
mitochondria (energy) and many vesicles that contain neurotransmitter
when the axon’s wave of depolarization reaches the synaptic knob, what happens
calcium channels open in the cellular membrane, causing an influx of calcium into the synaptic knob
The influx of calcium to the synaptic knob causes what?
vesicles containing neurotransmitters to fuse with the knob’s cellular membrane and dump their contents into the synaptic cleft
neurotransmitters diffuse rapidly across the ______ toward the _________
synaptic cleft
postsynaptic membrane
specialized proteins on the postsynaptic membrane
receptors
the neurotransmitter molecules released by the synaptic knob bind to what and trigger a change in the postsynaptic cell
receptors
neurotransmitters and receptors act as what
lock and key
what are the two categories of neurotransmitters
excitatory and inhibitory
usually cause an influx of sodium so that postsynaptic membrane moves toward the threshold, begin a new nerve impulse
excitatory neurotransmitters
make the inside of the cell more negative instead of positive and moving the charge within the postsynaptic cell farther away from the threshold
inhibitory neurotransmitters
neurotransmitter that can be either an excitatory or inhibitory neurotransmitter, depending on its location in the body
the most commonly studied neurotransmitter
acetylcholine
what neurotransmitters make up the group called catecholamines
norepinephrine, dopamine, epinephrine
neurotransmitter associated with arousal and fight or flight reactions of the sympathetic nervous system
norepinephrine
released primarily from the adrenal medulla (center of the adrenal gland), plays a role in fight or flight reactions
epinephrine
found in the brain where it is involved with autonomic functions and muscle control
dopamine
two neurotransmitters that are inhibitory
GABA and glycine
inhibitory neurotransmitter found in the brain
GABA
inhibitory neurotransmitter found in the spinal cord
glycine
what drug works as a tranquilizer due to increasing the GABA effect on the brain
diazepam (valium)