The sick preterm infant Flashcards

1
Q

Define:

  • Preterm
  • Term
  • Post term
A

-birth occurring before 37 wks gestation
-birth between 37 wks and 42 wks gestation
-birth after 42 wks gestation
(can’t survive before 23 wks)

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2
Q

risk factors for prematurity? (4)

A
  • More than 2 preterm deliveries
  • abnormally shaped uterus
  • maternal age
  • smoking, drinking, illicit drugs
  • poor nutrition, some chronic conditions e.g. high BP/diabetes
  • multiple miscarriages/abortions
  • multiple pregnancy
  • interval less than 6 months between pregnancies
  • IVF
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3
Q

Causes of preterm birth? (7)

A
  • spontaneous preterm labour
  • multiple pregnancy
  • preterm pre labour rupture of membranes
  • pregnancy assoc hypertension
  • IUGR
  • Antepartum haemorrhage
  • cervical incompetence/uterine malformation
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4
Q

What predisposes prem babies to illness?

A
  • get cold more quickly
  • more fragile lungs
  • don’t breath effectively
  • have fewer reserves
  • pulse oximetry often indicated
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5
Q

Explain assistance vs resuscitation?

A

few preterm babies will be asphyxiated need to keep them in good condition while helping to establish air breathing

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6
Q

Should cord clamping occur immediately?

-when?

A

If they baby is in good condition then can wait and allow placental transfusion to take place but need to keep the baby warm!

-when the physiological pulsing of the cord stops

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7
Q

How do we keep prem babies warm?

A

place them immediately (while still wet) into a plastic bag and under a radiant heater

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8
Q

Risk of over inflating prem lungs?

A

If you overinflated them you are likely to damage the tissue setting in motion an inflammatory cascade which will predispose to bronchopulmonary dysplasia

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9
Q

List the common concerns in a preterm infant

A
  • temp control
  • feeding/nutrition
  • sepsis
  • system immaturity/dysfunction (RDS, PDA, IVH, NEC)
  • other: metabolic, ROP
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10
Q

why is thermoregulation ineffective in the newborn?

  • name the 4 methods of heat loss
  • name methods to prevent heat loss
  • risk of incubator?
A
  • Low BMR
  • Minimal muscular activity
  • subcut fat insulation negligible
  • high ratio of SA to body mass
  • conduction, radiation, convection, evaporation
  • bags, skin to skin care, transwarmer mattress, prewarmed incubator
  • increased risk of infection was warm wet environment for bacteria
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11
Q

growth and nutrition

  • why is nutritional compromise more likely? (3)
  • what is gestational correction?
A
  • limited nutrient reserves, immature metabolic pathways and increased nutrient demands
  • adjusts the plot of a measurement to account for the number weeks a baby was born early, continue this until: 1 yr for 32-36 wks, 2 yrs for <32 weeks
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12
Q

Neonatal sepsis

  • onset?
  • organisms causing neonatal sepsis
  • Management
A
-can be:
early onset 
mainly due to bacteria acquired before and during delivery
Late onset
acquired after delivery 

-Group B strep
Gram negative organisms (Klebsialla, Escherichia coli, Pseuomonas and salmonella)
Gram positive organisms
(Staph aureus, Coagulase neg staph, strep pneumonia, strep pyogenes)
-Prevention/hand washing/vigilance/optimum supportive measures/ antibiotics

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13
Q

respiratory complications of prematurity:

-name the 3 main problems

A

-respiratory distress syndrome
Apnoea of prematurity
Bonchopulmonary dysplasia

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14
Q

Respiratory distress syndrome

  • definition
  • pathology
  • clinical features
  • management
  • complication
A

-Hyaline membrane disease

-Primary pathology:
surfactant deficiency, structural immature
secondary pathology, Alveolar damage, formation of exudate from leaky capillaries, inflammation, repair

-tachypnoea, grunting, intercostal recession, nasal flaring, cyanosis
these worsen over minutes to hours
ground glass appearance on X-ray

-maternal steroid, surfactant, ventilation, invasive/ non invasive ventilation
tend to use umbilical veins to put lines in

-tension pneumothorax

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15
Q

Cardiovascular concerns

-name the 2 major concerns

A

-patent ductus arteriosus, systemic hypotension

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16
Q

Patent ductus arteriosus

  • what is it?
  • symptoms?
A
  • ductus arterioles doesn’t close as the musculature is just not there
  • of congestive heart failure with high oxygen requirements and exacerbation of RDS
17
Q

Intraventricular haemorrhage

  • what is it?
  • risk factors?
  • monitering
  • preventative measures
  • grades?
A

-form of intracranial haemorrhage that occurs in preterm infants which begins with bleeding into the germinal matrix
large blood supply to the ventricles so can result on heamodynamic instability

-prematurity , resp distress syndrome
(hypoxia, acidosis + hypotension make unstable cerebral circulation more likely

  • moniter the bleed via the anterior fontanelle US
  • antenatal steroids, prompt and appropriate resuscitation, avoid heamodynamic instability, avoid: hypoxia, hypercarbia, hyperoxia and hypocarbia

-grades 1-4:
grades 1&2- neurodevelopment delay up to 20%, 10% mortality
grades 3&4- neurodevelopment delay to 80%, mortality 50%

18
Q

Necrotising enterocolitis

  • what is it?
  • presentation?
  • management?
A

-widespread necrosis in the small and large intestine

-usually after recovering from RDS
early signs include lethargy and gastric residuals
bloody stool, bradycardia, apnoea, temp instability
distended abdomen + jaundice

-feed with breast milk as this is easier for prem baby to digest

19
Q

other complications of prematurity?

  • neurodevelopmental outcome?
  • chronic health issues?
  • growth issues?
  • effect on adult health?
A

-retinopathy of prematurity (6-8 wks after prematurity)
-early- hypoglycaemia and hyponatraemia (lose Na in urine)
late- osteopenia of prematurity

  • impaired cognitive skills & motor deficits (fine or gross motor delay, cerebral palsy, sensory impairment including vision and hearing losses, behavioural and psychological problems)
  • higher rates of chronic conditions
  • more likely to exhibit poor growth
  • insulin resistance, hypertension and vascular changes assoc with decreased reproduction in adulthood + preterm risk of preterm offspring