breast imaging Flashcards

1
Q

when is imaging needed?

  • if presenting with pain?
  • if presenting with Mass?
A
-in symptomatic patients with: 
Lumps
Unilateral or blood-stained nipple discharge
Skin tethering or dimpling
Signs of inflammation
Axillary lumps

As screening

-only if assoc with focal/asymmetric nodularity, US and/or Mammogram

-US if <40
Mammogram
+/- US if >40

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2
Q

what is the triple assessment approach in breast cancer

A

Clinical examination
imaging- mammogram/US
pathology- i.e biopsy

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3
Q

name the 3 main imaging modalities in breast?

A

Mammography- film or digital
US
MRI?

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4
Q

Mammography

-why is it the primary form of imaging?

A

-cost effective & non invasive
reproducible
reliably visualises micro calcifications

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5
Q

where is digital mammography an advantage?

-adv?

A

-in dense breasts and younger women, gives excellent contrast resolution

-better contrast
shorter exam time
fewer technical repeats
fewer films
easier image storage and transfer
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6
Q

What do you look for on a normal mammogram?

A
skin and pores
Fat-low density (dark)
glandular density (appears lighter)
blood vessels and vascular calcifications
Lymph nodes (oval/horseshoe)
Calcifications- appear bright white
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7
Q

List the 3 main mammography views

A

Mediolateral oblique (MLO)- table at a 45 deg angle off vertical
Craniocaudal (CC)- table horizontal
Extended CC

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8
Q

What is the BIRADS classification for?

give the 4 categories

A

A measure of breast density

a: nearly all fat
b: scattered fibroglandular densities (25-50%)
c: heterogeneously dense (51-75% glandular)
d: extremely dense (> 75% glandular)

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9
Q

features of malignant calcification?
distribution
cluster/size shape individual particle shape
Pleomorphic nature

A
  • cluster or segmental is suspicious Vs scattered or diffuse (benign)
  • rhomboid forms, worry if looks like it follows ductal system
  • linear/brnaching/Y-shaped
  • size, density
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10
Q

effect of HRT on breast tissue?

A

causes the tissue to become more dense

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11
Q

indications for US?

-area scanned?

A
for the characterisation of mammography lesions- lesions cystic or solid?
palpable lesions in women <40
nipple discharge
breast implant
inflammatory conditions 
to evaluate response to chemo

-scan along the ductal system and perpendicular to it

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12
Q

features of a benign lesion on US?

malignant lesion?

A
-circumscribed
hypo/hyperechoic
wider than tall
homogeneous
peripheral/no vascularity
often multiple
-poorly circumscribed
Hypoechioc
Heterogeneous
Taller than wide
Speculate
Oedema/peritumoral fat
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13
Q

Vacuum assisted biopsy

  • describe
  • what might need to be done after biopsy?
A
  • tissue is sucked into a chamber and then cut and sucked into a collecting pot.
  • the whole tumour might be removed in which case you need to deploy a marker
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14
Q

why is MRI effective?

A
Excellent intrinsic tissue contrast
multiplayer tomographic capacity
No compression
No ionising radiation
Accuracy independent of breast density
can use IV gadolinium based contrast
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15
Q

interpretation of breast MRI:

  • what to look for?
  • 6 morphological features?
  • indications?
  • contraindications?
  • diasadv?
A

-any enhancement? does it show a mass or not?
Morphology?
Rate of enhancement

-smooth mass
non enhancing internal septations
ductal enhancement
Rim enhancement
irregular mass
Speculated mass

-benign: implants, ,lesion characterisation
Malignant: dx, staging an treatment plan, residual disease, asses response, recurrent disease, screening in high risk groups

-absolute:
pacemakers, cochlear implants, renal impairment etc
Relative:
Pregnancy, lactation
the effect of the gadolinium based contrast and increased background breast enhancement

-patient acceptability/tolerance
over diagnosis
hard to localise and biopsy lesions seen on MR only
cost and access in appropriate time frame

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16
Q

name the high risk groups for screening

A

prev irradiation (particularly in childhood)
BRCA 1/2
TP 53 mutations
personal hx breast cancer